Results 51 to 60 of about 15,033 (230)
Immunometabolic control of hematopoiesis
Molecular Aspects of Medicine, 2021 Hematopoietic stem cells (HSC) lie at the center of the hematopoiesis process, as they bear capacity to self-renew and generate all hematopoietic lineages, hence, all mature blood cells. The ability of HSCs to recognize systemic infection or inflammation or other forms of peripheral stress, such as blood loss, is essential for demand-adapted ...
George Hajishengallis +2 more
openaire +3 more sources
Mitochondrial Control and Guidance of Cellular Activities of T Cells. [PDF]
, 2017 Immune cells protect us against infection and cancer cells, as well as functioning during healing processes to support tissue repairing and regeneration.
Chao, T., Ho, P.C., Wang, H.
core +1 more source
Ironing out Macrophage Immunometabolism [PDF]
Pharmaceuticals, 2019 Over the last decade, increasing evidence has reinforced the key role of metabolic reprogramming in macrophage activation. In addition to supporting the specific immune response of different subsets of macrophages, intracellular metabolic pathways also directly control the specialized effector functions of immune cells. In this context, iron metabolism
Recalcati, Stefania +2 more
openaire +4 more sources
Distinct blood and visceral adipose tissue regulatory T cell and innate lymphocyte profiles characterize obesity and colorectal cancer [PDF]
, 2017 Visceral adipose tissue (VAT) is a main site where metabolic and immunologic processes interplay to regulate, at local and systemic level, the inflammatory status and immune response.
Barbara Varano +14 more
core +2 more sources
Materials Today Bio, 2023 Cardiovascular disease remains the leading cause of death and morbidity worldwide. Inflammatory responses after percutaneous coronary intervention led to neoathrosclerosis and in-stent restenosis and thus increase the risk of adverse clinical outcomes ...
Yuanyuan Cui +11 more
doaj +1 more source
Biochemical Underpinnings of Immune Cell Metabolic Phenotypes [PDF]
, 2017 The metabolism of immune cells affects their function and influences host immunity. This review explores how immune cell metabolic phenotypes reflect biochemical dependencies and highlights evidence that both the metabolic state of immune cells and ...
Olenchock, Benjamin A. +2 more
core +1 more source
Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function
, 2018 Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the synthesis of macromolecules and ...
Pearce, E., Rambold, A.
core +1 more source
Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]
, 2018 Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara +5 more
core +2 more sources
Microglial Immunometabolism in Alzheimer’s Disease [PDF]
Frontiers in Cellular Neuroscience, 2020 Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid-β (Aβ) plaques and the formation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau. In response to Aβ and tau aggregates, microglia, the primary innate immune cells of the central nervous system (CNS), facilitate Aβ and tau clearance and contribute to ...
Daniel C. Shippy, Tyler K. Ulland
openaire +3 more sources
Frontiers in Immunology, 2022 Clear cell renal cell carcinoma (ccRCC) is characterized by metabolic dysregulation and distinct immunological signatures. The interplay between metabolic and immune processes in the tumor microenvironment (TME) causes the complexity and heterogeneity of
Yi Wang +13 more
doaj +1 more source