Results 41 to 50 of about 74,853 (208)

Bifidobacteria BbC50 Fermentation Products Induce Human Cd4 Regulatory T Cells with Antigen-Specific Activation and Bystander Suppression

European Journal of Inflammation, 2014
Probiotic bacteria have been shown to have health benefits in various situations (inflammation, allergy, infection). We previously showed that a bacteria-free fermentation product of Bifidobacterium breve C50 (BbC50sn) induced high IL-10 secretion by ...
L. Martin, A. Granier, R. Lemoine, A. Dauba, S. Vermeersch, C. Aubert-Jacquin, C. Baron, Y. Lebranchu, C. Hoarau, F. Velge-Roussel   +9 more
doaj   +1 more source

Global scientific trends on the immunomodulation of mesenchymal stem cells in the 21st century: A bibliometric and visualized analysis

Frontiers in Immunology, 2022
BackgroundSince the discovery of the immunomodulatory functions of mesenchymal stem cells (MSCs), their application in immunomodulation has attracted considerable attention, and an increasing number of studies have been conducted worldwide.
Zhongqing Wang, Yuqiang Sun, Rou Shen, Rou Shen, Xia Tang, Xia Tang, Yingxin Xu, Ye Zhang, Yao Liu, Yao Liu   +9 more
doaj   +1 more source

Analysis of multivariate longitudinal immuno-epidemiological data using a pairwise joint modelling approach

BMC Immunology, 2021
Background Immuno-epidemiologists are often faced with multivariate outcomes, measured repeatedly over time. Such data are characterised by complex inter- and intra-outcome relationships which must be accounted for during analysis.
Lawrence Lubyayi, Patrice A. Mawa, Stephen Cose, Alison M. Elliott, Jonathan Levin, Emily L. Webb   +5 more
doaj   +1 more source

Immunomodulation—a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system

Frontiers in Immunology, 2023
In recent years, there has been a tremendous development of biotechnological, pharmacological, and medical techniques which can be implemented in the functional modulation of the immune system components.
Martyna Strzelec, Jan Detka, Patrycja Mieszczak, Małgorzata Katarzyna Sobocińska, Marcin Majka   +4 more
doaj   +1 more source

Effect of immunomodulation on cardiac remodelling and outcomes in heart failure: a quantitative synthesis of the literature

ESC Heart Failure, 2020
Aims Immunomodulation in heart failure (HF) has been studied in several randomized controlled trials (RCTs) with variable effects on cardiac structure, function, and outcomes.
Navkaranbir S. Bajaj, Kartik Gupta, Nitin Gharpure, Mike Pate, Lakshay Chopra, Rajat Kalra, Sumanth D. Prabhu   +6 more
doaj   +1 more source

Ethnobotanical survey, anthelmintic effects and cytotoxicity of plants used for treatment of helminthiasis in the Central and Kara regions of Togo

BMC Complementary Medicine and Therapies, 2020
Background Traditional medicines are the main source of treatment of helminthiasis in endemic areas of Togo. The present study aimed to investigate the plants used by Traditional healers (THs) to treat helminth infections in endemic communities within ...
Essoham Ataba, Gnatoulma Katawa, Manuel Ritter, Adjoa Holali Ameyapoh, Kokou Anani, Oukoe M. Amessoudji, Pélagie Edlom Tchadié, Tchadjabo Tchacondo, Komlan Batawila, Yaovi Ameyapoh, Achim Hoerauf, Laura E. Layland, Simplice D. Karou   +12 more
doaj   +1 more source

Pyroptosis: Physiological roles in viral infection [PDF]

arXiv, 2020
The current review focuses on important aspects of pyroptosis, such as morphological features of inflammasomes, as well as on knowledge about coronavirus infection mechanisms and the association between SARS-CoV-2 infection and cell pyroptosis. The application of immunomodulation therapies to Covid-19 patients is the most promising treatment under ...
arxiv  

Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda

npj Vaccines
Vaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in
Jacent Nassuuna, Joas Sterk, Bridgious Walusimbi, Agnes Natukunda, Ronald Nkangi, Rebecca Amongin, Ludoviko Zirimenya, Emily L. Webb, Alison M. Elliott, Gyaviira Nkurunungi   +9 more
doaj   +1 more source

Antileishmanial Activity of Flavones-Rich Fraction From Arrabidaea chica Verlot (Bignoniaceae)

Frontiers in Pharmacology, 2021
Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of flavones from Arrabidaea chica against L. amazonensis.
João Victor Silva-Silva, Carla Junqueira Moragas-Tellis, Maria do Socorro dos Santos Chagas, Paulo Victor Ramos de Souza, Paulo Victor Ramos de Souza, Celeste da Silva Freitas de Souza, Daiana de Jesus Hardoim, Noemi Nosomi Taniwaki, Davyson de Lima Moreira, Maria Dutra Behrens, Kátia da Silva Calabrese, Fernando Almeida-Souza, Fernando Almeida-Souza   +12 more
doaj   +1 more source

Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function

Cells
Regulatory T cells (Tregs) are essential to maintain immune homeostasis by promoting self-tolerance. Reduced Treg numbers or functionality can lead to a loss of tolerance, increasing the risk of developing autoimmune diseases.
Chelsea Gootjes, Jaap Jan Zwaginga, Bart O. Roep, Tatjana Nikolic   +3 more
doaj   +1 more source