Results 41 to 50 of about 142,022 (295)

The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease [PDF]

open access: yes, 2010
The dramatic recent rise in the incidence of allergic or autoimmune inflammatory diseases in the West has been proposed to reflect the lack of appropriate priming of the immune response by infectious agents such as parasitic worms during childhood ...
Al-Riyami   +111 more
core   +2 more sources

Spirochetal Lipoproteins and Immune Evasion. [PDF]

open access: yes, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani   +2 more
core   +1 more source

Ethnobotanical survey, anthelmintic effects and cytotoxicity of plants used for treatment of helminthiasis in the Central and Kara regions of Togo

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Traditional medicines are the main source of treatment of helminthiasis in endemic areas of Togo. The present study aimed to investigate the plants used by Traditional healers (THs) to treat helminth infections in endemic communities within ...
Essoham Ataba   +12 more
doaj   +1 more source

Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity [PDF]

open access: yes, 2018
Transfusion of red cell concentrates (RCCs) is associated with increased risk of adverse outcomes that may be affected by different blood manufacturing methods and the presence of extracellular vesicles (EVs).
Acker, Jason P.   +9 more
core   +3 more sources

Global scientific trends on the immunomodulation of mesenchymal stem cells in the 21st century: A bibliometric and visualized analysis

open access: yesFrontiers in Immunology, 2022
BackgroundSince the discovery of the immunomodulatory functions of mesenchymal stem cells (MSCs), their application in immunomodulation has attracted considerable attention, and an increasing number of studies have been conducted worldwide.
Zhongqing Wang   +9 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Analysis of multivariate longitudinal immuno-epidemiological data using a pairwise joint modelling approach

open access: yesBMC Immunology, 2021
Background Immuno-epidemiologists are often faced with multivariate outcomes, measured repeatedly over time. Such data are characterised by complex inter- and intra-outcome relationships which must be accounted for during analysis.
Lawrence Lubyayi   +5 more
doaj   +1 more source

Human Schistosome Infection and Allergic Sensitisation [PDF]

open access: yes, 2012
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Mutapi, Francisca   +2 more
core   +3 more sources

Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang   +16 more
wiley   +1 more source

Antileishmanial Activity of Flavones-Rich Fraction From Arrabidaea chica Verlot (Bignoniaceae)

open access: yesFrontiers in Pharmacology, 2021
Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of flavones from Arrabidaea chica against L. amazonensis.
João Victor Silva-Silva   +12 more
doaj   +1 more source

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