Results 121 to 130 of about 4,214 (170)

Intracellular Activation of Dual-Pharmacophore Artezomib Enhances Selective Cytotoxicity in Hematologic Malignancies. [PDF]

J Med Chem
Li D, Huang X, Chow Z, Ye J, Ma R, Zhu M, Jayabalan D, Zhang H, Zhou P, Chen-Kiang S, Niesvizky R, Lin G.   +11 more
europepmc   +1 more source

Ubiquitin-conjugating enzyme UBE2N modulates proteostasis in immunoproteasome-positive acute myeloid leukemia. [PDF]

J Clin Invest
Ishikawa C, Barreyro L, Sampson AM, Hueneman KM, Choi K, Philbrook SY, Choi I, Bolanos LC, Wunderlich M, Volk AG, Watowich SS, Greis KD, Starczynowski DT.   +12 more
europepmc   +1 more source

Protein translation dysregulation and immune cell evasion mediated by IFN and immunoproteasome downregulation define metastatic clones in HPV-related cancer of the oropharynx. [PDF]

BMC Med
Chin VT, Muskovic W, McCloy RA, Neavin DR, Alquicira-Hernandez J, Arora H, Senabouth A, Sudhakar KK, Keith P, Spenceley E, Kaczorowski D, Floros P, Leavers B, Crawford JA, Gallagher R, Powell JE.   +15 more
europepmc   +1 more source

Repurposing Carfilzomib as a Promising Drug for Targeted Therapy in Gastric Cancer. [PDF]

Cancers (Basel)
Kurstjens EM, Cox KE, Bali P, Amirfakhri S, Hernandez J, Lozano-Pope I, Benner C, Bouvet M, Obonyo M.   +8 more
europepmc   +1 more source

Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation. [PDF]

Cell Rep Med
Sagie S, Babu T, Weller C, Tabachnik C, Livneh I, Quast NP, Gumpert N, Shomuradova A, Raybould MI, Levy R, Malko D, Alfia A, Ben Lulu T, Alon M, Herrera F, Kutuzov M, Zerbib M, Greenberg P, Wasserman-Bartov T, Benedek G, Levin Y, Stossel C, Kamer I, Golan T, Oren R, Shmueli M, Bartok O, Bar J, Cohen J, Dushek O, Deane CM, Samuels Y.   +31 more
europepmc   +1 more source

Proteomics Reveals Differential Diagnosis Biomarkers Between Sepsis and Hemophagocytic Syndrome. [PDF]

Biomedicines
Martin-Pestana D, Azkargorta M, Pilar-Orive FJ, Redondo S, Urrutia J, Calvo C, Elortza F, Astigarraga I, Garcia-Obregon S.   +8 more
europepmc   +1 more source

The Role of the Ubiquitin System in Eye Diseases. [PDF]

Life (Basel)
Durán-Cristiano SC, de Diego-García L, Martín-Gil A, Carracedo G.   +3 more
europepmc   +1 more source

Global perspectives on lupus nephritis: a review of clinical trials and therapeutic innovations. [PDF]

Front Immunol
Xu J, Zhang Y, Huang H, Cao Y.
europepmc   +1 more source

PI31 is a positive regulator of 20S immunoproteasome assembly.

J Cell Sci
Wang J, Kjellgren A, DeMartino GN.
europepmc   +1 more source

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Immunoproteasomes and immunosenescence

Ageing Research Reviews, 2003
Aging is a complex process which is accompanied with the decline and the reshaping of different functions of the body. In particular the immune system is characterized, during ageing (immunosenescence) by a remodeling of innate immunity (well preserved, up-regulated) and clonotypical immunity (severely altered) and by the occurrence of a chronic ...
Mishto M., Santoro A., Bellavista E., Bonafe M., Monti D., Franceschi C.   +5 more
openaire   +3 more sources