Results 121 to 130 of about 8,916 (246)

Circulating proteasome activity following mild head injury in children [PDF]

open access: yes, 2014
PURPOSE: The aim of the study is to characterize changes in circulating proteasome (c-proteasome) activity following mild traumatic brain injury in children.
Adam Hermanowicz   +4 more
core   +1 more source

Buffered memory: a hypothesis for the maintenance of functional, virus-specific CD8(+) T cells during cytomegalovirus infection. [PDF]

open access: yes, 2011
Chronic infections have been a major topic of investigation in recent years, but the mechanisms that dictate whether or not a pathogen is successfully controlled are incompletely understood.
A Marchant   +82 more
core   +2 more sources

Targeting Immunoproteasome in Polarized Macrophages Ameliorates Experimental Emphysema Via Activating NRF1/2‐P62 Axis and Suppressing IRF4 Transcription

open access: yesAdvanced Science
Chronic obstructive pulmonary disease (COPD) stands as the prevailing chronic airway ailment, characterized by chronic bronchitis and emphysema. Current medications fall short in treatment of these diseases, underscoring the urgent need for effective ...
Bingxin Guo   +20 more
doaj   +1 more source

Subversion of immunoproteasome subunit expression in dengue virus serotype 2-infected HepG2 cells

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
: INTRODUCTION: Infection with all serotypes of dengue virus (DV) results in augmented antigen presentation by MHC class I molecules. However, the upregulation of immunoproteasome subunits only results from infection with two serotypes. This study aims
Chye Sheng Gan   +4 more
doaj   +1 more source

A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm [PDF]

open access: yes, 2012
Uterine leiomyosarcoma (ULMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine ULMS
Akiko Horiuchi   +5 more
core   +1 more source

Sequence Variants in PSMB8/PSMB9 Immunoproteasome Genes and Risk of Urothelial Bladder Carcinoma [PDF]

open access: diamond, 2023
Nasser A. Elhawary   +10 more
openalex   +1 more source

Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. [PDF]

open access: yes, 2016
The reduction of oxidative stress is suggested to be one of the main mechanisms to explain the benefits of subnormothermic perfusion against ischemic liver damage. In this study we investigated the early cellular mechanisms induced in isolated rat livers
Alva, Norma   +4 more
core   +4 more sources

A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells [PDF]

open access: bronze, 2012
Stuart P. Atkinson   +6 more
openalex   +1 more source

Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders

open access: yesEBioMedicine, 2018
Accumulation of aggregated α-synuclein into Lewy bodies is thought to contribute to the onset and progression of dopaminergic neuron degeneration in Parkinson's disease (PD) and related disorders.
Scott Ugras   +14 more
doaj   +1 more source

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