Results 41 to 50 of about 3,957 (191)
The International Journal of Biological Markers, 2019 Purpose: This study aimed to elucidate the clinicopathological significance and prognostic role of tumor-infiltrating lymphocytes in colorectal cancer. Methods: The immunohistochemistry of CD3 and CD8 was performed on 265 human colorectal cancer tissues ...
Young San Ko, Jung-Soo Pyo
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Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy [PDF]
Cancer Immunology Research, 2016 Abstract Tumor immunoscore analyses, especially for primary colorectal cancer and melanoma lesions, provide valuable prognostic information. Metastatic lesions of many carcinoma types, however, are often not easily accessible. We hypothesized that immune cells in peripheral blood may differ among individual patients with metastatic ...
Benedetto, Farsaci +11 more
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Classification of early-stage colon cancer with Immunoscore (R): clinical evidence and case studies
, 2022 Immunoscore (R) is a digital pathology diagnostic immunoassay used to complement tumor node metastasis staging for the prediction of recurrence risk in patients with early-stage colon cancer.
Athanasiadis, Ilias +4 more
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Profiles of Immune Infiltration and Prognostic Immunoscore in Lung Adenocarcinoma [PDF]
BioMed Research International, 2020 Lung tissue is abundant with immune cells that form a powerful first defense against exotic particles and microbes. The malignant phenotype of lung adenocarcinoma (LUAD) is defined not only by intrinsic tumor cells but also by tumor‐infiltrating immune cells (TIICs) recruited to the immune microenvironment.
Yanyan Li, Liping Tao, Weiyang Cai
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Frontiers in Immunology, 2020 Colorectal cancer occurrence and progression involve multiple aspects of host immune deficiencies. In these events, immune cells vary their phenotypes and functions over time, thus enabling the immune microenvironment to be “tumor-inhibiting” as well as “
Liang Guo +6 more
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Frontiers in Immunology, 2022 Tumor microenvironment (TME) includes a wide variety of cell types and soluble factors capable of suppressing immune-responses. While the role of NK cells in TME has been analyzed, limited information is available on the presence and the effect of ...
Nicola Tumino +19 more
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Immunoscore in mismatch repair‐proficient and ‐deficient colon cancer
The Journal of Pathology: Clinical Research, 2017 AbstractThe aim of this study was to investigate immune response and its prognostic significance in colon carcinomas using the previously described Immunoscore (IS). A population‐based series of 779 colorectal cancers, operated on between 2000 and 2010, were classified according to tumour, node, metastasis (TNM) status, mismatch repair (MMR), and BRAF ...
Wirta, Erkki-Ville +10 more
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Prognostic Impact of YKL-40 Immunohistochemical Expression in Patients with Colorectal Cancer
Current Oncology, 2021 This study aims to examine the clinicopathological and prognostic significance of the YKL-40 immunohistochemical expression of tumor and immune cells through human colorectal cancer (CRC) tissue.
Il Hwan Oh +2 more
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Immunoscore in 3D tissue [PDF]
, 2020 Solid tumors are complex structures comprising besides the cancer cells vasculature, extracellular matrix (ECM), soluble molecules and a plethora of various other cell types. These components form a so-called tumour microenvironment.
Novák, Jaromír
core
The landscape and prognostic value of tumor-infiltrating immune cells in gastric cancer [PDF]
PeerJ, 2019 Background Gastric cancer (GC) is the fourth most frequently diagnosed malignancy and the second leading cause of cancer-associated mortality worldwide.
Linhai Li +4 more
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