Results 81 to 90 of about 3,200 (166)

The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
N6‐methyladenosine RNA methylation regulators are intricately linked with the development of polycystic ovary syndrome (PCOS) and may influence immune cell infiltration in affected individuals. This study enhances our understanding of the molecular interactions in PCOS and suggests potential biomarkers for diagnosis and targets for therapeutic ...
Wenting Xu, Lingli Shi, Aifang Lu, Lijuan Cui, Haiqing Qian, Jiahui Wang, Mengyu Tang, Lili Zhu, Lihong Wang   +8 more
wiley   +1 more source

Immunoscore Signature Predicts Postoperative Survival and Adjuvant Chemotherapeutic Benefits in Esophageal Squamous Cell Carcinoma

Cancer Management and Research, 2020
Lingdun Zhuge,1,2,* Binhao Huang,1,2,* Juntao Xie,1,2 Zhendong Gao,1,2 Difan Zheng,1,2 Shanbo Zheng,1,2 Jiaqing Xiang,1,2 Jie Zhang3 1Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, People’s Republic of China ...
Zhuge L, Huang B, Xie J, Gao Z, Zheng D, Zheng S, Xiang J, Zhang J   +7 more
doaj  

Immunoscore for (colorectal) cancer precision medicine [PDF]

The Lancet, 2018
Shuji, Ogino, Marios, Giannakis
openaire   +2 more sources

CD3+ and CD8+ T cell-based immune cell score as a prognostic factor in clear-cell renal cell carcinoma

Acta Oncologica
Background and purpose: Immunoscore® is a prognostic parameter based on densities of lymphocyte populations in the tumor center and invasive margin. Immunoscore® is validated in colorectal cancer as a high Immunoscore® is associated with longer survival.
Jonne Åkerla, Olli Helminen, Juha P. Väyrynen, Anne Parkkinen, Hilma Järvenpää, Jan Böhm, Maarit Ahtiainen, Heikki Seikkula   +7 more
doaj   +1 more source

Quantifying Immunoscore performance – Authors' reply [PDF]

The Lancet, 2018
Franck, Pagès, Bernhard, Mlecnik, Jérôme, Galon   +2 more
openaire   +2 more sources

Immunoscore: redefining the landscape of colorectal cancer control and care

Future Oncology
The Immunoscore (IS), introduced by Jerome Galon in the early 2000s, evaluates immune cell densities within tumors, offering a more accurate prediction of clinical outcomes in colorectal cancer (CRC) compared to the TNM system. Studies have demonstrated that IS enhances the prediction of recurrence, disease-free survival, and overall survival in early ...
John Zakhour, Maria Njeim, Rita Haddad, Joseph Akiki, Clara Njeim, Nicolas Nakouzi, Michel Rustom, Elias Karam, Carole Kesrouani, Joseph Gharios, Hampig Raphael Kourie   +10 more
openaire   +2 more sources

Classificação Immunoscore em Carcinoma Colorretal

, 2023
Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de ...
openaire   +1 more source

Immunochemistry-based quantification of tumor-infiltrating lymphocytes and immunoscore as prognostic biomarkers in bladder cancer

Journal of the Egyptian National Cancer Institute
Background Tumor-infiltrating lymphocytes (TILs) and the derived immunoscore (IS) have gained considerable attention over the last decade as prognostic markers in many solid cancers.
Sarra Ben Rejeb, Sirine Elfekih, Nadia Kouki, Rami Boulma, Hassen Khouni   +4 more
doaj   +1 more source

Near future of tumor immunology: Anticipating resistance mechanisms to immunotherapies, a big challenge for clinical trials

Human Vaccines & Immunotherapeutics, 2017
The success of immunotherapies brings hope for the future of cancer treatment. Even so, we are faced with a new challenge, that of understanding which patients will respond initially and, possibly, develop resistance.
João Paulo Portela Catani, Rachel P. Riechelmann, Sandy Adjemian, Bryan E. Strauss   +3 more
doaj   +1 more source

[Recent Advances in Peripheral Immunoscore in Lung Cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer
Lung cancer is the malignant tumor with the highest morbidity and mortality. The tumor-node-metastasis (TNM) staging has gradually shown its limitations in the accurate prediction of lung cancer, so it is urgent to construct a new clinical predictive model to guide the prevention and treatment of lung cancer.
Fan XU, Bin LUO, Jianhui TIAN, Yun YANG, Zhenyang CHENG, Youjun LIU   +5 more
openaire   +2 more sources