Results 211 to 220 of about 514,735 (343)

IMMUNOSUPPRESSION WITH AZATHIOPRINE, PREDNISONE, AND CYCLOPHOSPHAMIDE1

, 1979
John Jeffery, Allan R. Downs, CHARLES LYE, Ernest W. Ramsey   +3 more
openalex   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

A molecular systems architecture of the mesenchymal stromal cell microenvironment. [PDF]

Stem Cells
Ayyadurai VAS, Deonikar P, Radhakrishnan V, Keating A.   +3 more
europepmc   +1 more source

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

Advanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang, Feifei Li, Libo Liu, Ziyu An, Hanzhong Luo, Huan Zhang, Rui Ma, Ruoxi Zhang, Qiong Dai, Mingduo Zhang, Jinfan Tian, Chaoyong Liu, Xiantao Song, Yunfeng Lu   +13 more
wiley   +1 more source

THE EFFECTS OF PHYTOHEMAGGLUTININ AND ANTILYMPHOCYTE GLOBULIN IN INDUCING IMMUNOSUPPRESSION AND TOLERANCE IN MICE1,2

, 1971
NULL AUTHOR_ID
openalex   +2 more sources

THYMECTOMY AS IMMUNOSUPPRESSION IN UREMIC PATIENTS

, 1975
Sven Arvid Birkeland, J. Moesner, F Juhl, E Kemp, Henrik Sørensen   +4 more
openalex   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

Advanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho, Su Min Kim, Jiyeon Lee, Oh Chan Kwon, Wonjin Woo, Eunji Lee, Hyo Jin Park, Yeongun Lee, So Hee Dho, Tae‐Kyung Kim, Min‐Chan Park, Richard A. Flavell, Lark Kyun Kim   +12 more
wiley   +1 more source

Managing the failing renal allograft: navigating a complex topography. [PDF]

Front Nephrol
Kendrick EA.
europepmc   +1 more source

Cell migration, chimerism, and graft acceptance: with particular reference to the liver [PDF]

, 1996
Demetris, AJ, Murase, N, Ricordi, C, Starzl, TE, Trucco, M   +4 more
core  

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]

, 2018
Denner, Joachim, Schuurman, Henk-Jan, Scobie, Linda   +2 more
core   +1 more source