Results 1 to 10 of about 4,619,877 (335)

Comparisons Between Frontline Therapy and a Combination of Eltrombopag Plus Immunosuppression Therapy and Human Leukocyte Antigen-Haploidentical Hematopoietic Stem Cell Transplantation in Patients With Severe Aplastic Anemia: A Systematic Review [PDF]

Frontiers in Oncology, 2021
Background and Aims: This study aimed at comparing the efficacy and safety of eltrombopag (EPAG) plus immunosuppressive therapies (ISTs) and haploidentical hematopoietic stem cell transplantation (haplo-HSCT) in the frontline treatment for severe ...
Yuan Yang, Jiang Ji, Zengwei Tang, Bing Han   +3 more
doaj   +4 more sources

Living donor liver transplantation for autoimmune hepatitis in identical monozygotic twins: a case report [PDF]

Clinical Transplantation and Research
Liver transplantation (LT) is an effective treatment for end-stage liver diseases, including autoimmune hepatitis. Advances in immunosuppressive therapy have improved patient and graft survival; however, these treatments can cause serious side effects ...
Kulbhushan Haldeniya, Kausar Makki, Yogesh Yadav, Tathagata Karan, Nalini Kanta Ghosh, Piyush Srivastava, Anil Agarwal, Vivek Vij   +7 more
doaj   +2 more sources

Autoimmune encephalitis and epilepsy: evolving definition and clinical spectrum [PDF]

Clinical and Experimental Pediatrics, 2020
Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder.
Joo Hee Seo, Yun-Jin Lee, Ki Hyeong Lee, Elakkat Gireesh, Holly Skinner, Michael Westerveld   +5 more
doaj   +1 more source

Impact of COVID-19 on patients treated with autologous hematopoietic stem cell transplantation: A retrospective cohort study

Upsala Journal of Medical Sciences, 2022
Objective: To describe how coronavirus disease 2019 (COVID-19) affects patients with hematological malignancies treated with autologous hematopoietic stem cell transplantation (ASCT).
Thomas Silfverberg, Björn Wahlin, Kristina Carlson, Honar Cherif   +3 more
doaj   +1 more source

Impact of B Cell Depletion on COVID-19 in Kidney Transplant Recipients

Viruses, 2023
Kidney transplant recipients are patients at high risk for coronavirus disease 2019 (COVID-19) due to being on immunosuppressive therapy. B cell depletion therapy, including rituximab, is an important strategy for ABO-incompatible transplants.
Naohiro Aida, Taihei Ito, Kei Kurihara, Izumi Hiratsuka, Megumi Shibata, Atsushi Suzuki, Midori Hasegawa, Takashi Kenmochi   +7 more
doaj   +1 more source

Reactivation of Tumor-like Chagas Disease in the Central Nervous System in Cardiac Transplant Patients: A Case Series and Literature Review

Brazilian Neurosurgery, 2023
Introduction Chagas disease is an important public health problem in Latin American countries, affecting ∼ 6 million people within the region.
Antônio Gilson Prates Júnior, Fernando Augusto Medeiros Carrera Macedo, José Augusto Malheiros, Maria Letícia Marques Pinheiro, Lucas Rodrigues de Souza, Ana Luisa Ribeiro Pinto, Bruna Kelren Freitas Pohlmann   +6 more
doaj   +1 more source

Preventing kidney transplant failure by screening for antibodies against human leucocyte antigens followed by optimised immunosuppression: OuTSMART RCT

Efficacy and Mechanism Evaluation, 2023
Design Investigator-led, prospective, open-labelled marker-based strategy (hybrid) randomised trial. Background Allografts in 3% of kidney transplant patients fail annually.
Stringer Dominic, Gardner Leanne, Shaw Olivia, Clarke Brendan, Briggs David, Worthington Judith, Buckland Matthew, Hilton Rachel, Picton Michael, Thuraisingham Raj, Borrows Richard, Baker Richard, Tinch-Taylor Rose, Horne Robert, McCrone Paul, Kelly Joanna, Murphy Caroline, Peacock Janet, Dorling Anthony   +18 more
doaj   +1 more source

Case Report: A Case Series of Immunobiological Therapy (Anti-TNF-α) for Patients With Erythema Nodosum Leprosum

Frontiers in Medicine, 2022
Patients with leprosy may experience a chronic and severe type II leprosy reaction (ENL) erythema nodosum leprosum that may not respond to thalidomide and systemic immunosuppressants or may even cause serious adverse events. We here present four patients
Ana Flávia Moura Mendes, Ciro Martins Gomes, Patrícia Shu Kurizky, Mayra Ianhez, Mayra Ianhez   +4 more
doaj   +1 more source

Co Treatment With Biologic Agents and Immunotherapy in the Setting of irAEs of Difficult Management

Frontiers in Medicine, 2022
In recent years, immunotherapy has become an important pillar of cancer treatment, with high response rates regardless of tumor histology or baseline mutations, sometime in patients without any alternative of treatment.
Virginia Robles-Alonso, Fernando Martínez-Valle, Natalia Borruel, Natalia Borruel   +3 more
doaj   +1 more source

BK polyomavirus-associated nephropathy [PDF]

Childhood Kidney Diseases, 2022
BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft
Yo Han Ahn, Hee Gyung Kang
doaj   +1 more source