Results 11 to 20 of about 4,619,877 (335)

Immunosuppression therapy for idiopathic membranous nephropathy: systematic review with network meta-analysis. [PDF]

J Nephrol, 2022
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome in adults. The Kidney Disease Improving Global Outcomes guidelines recommend rituximab or cyclophosphamide and steroids, or calcineurin inhibitor-based therapy. However, there have
Bose B, Chung EYM, Hong R, Strippoli GFM, Johnson DW, Yang WL, Badve SV, Palmer SC.   +7 more
europepmc   +2 more sources

CD73 in small extracellular vesicles derived from HNSCC defines tumour‐associated immunosuppression mediated by macrophages in the microenvironment

Journal of Extracellular Vesicles, 2022
Research on tumour cell‐derived small extracellular vesicles (sEVs) that regulate tumour microenvironment (TME) has provided strategies for targeted therapy of head and neck squamous cell carcinoma (HNSCC).
Tingwei Lu, Zhen Zhang, Jianjun Zhang, Xinhua Pan, Xueqin Zhu, Xu Wang, Zhihui Li, Min Ruan, Huasheng Li, Wantao Chen, Ming Yan   +10 more
doaj   +2 more sources

Center-driven and Clinically Driven Variation in US Liver Transplant Maintenance Immunosuppression Therapy: A National Practice Patterns Analysis. [PDF]

Transplant Direct, 2018
Background Variation in the use of immunosuppression regimens after liver transplant has not been well described. Methods Immunosuppression regimens used after liver transplant were identified in a novel database integrating national transplant registry ...
Nazzal M, Lentine KL, Naik AS, Ouseph R, Schnitzler MA, Zhang Z, Randall H, Dharnidharka VR, Segev DL, Kasiske BL, Hess GP, Alhamad T, McAdams-Demarco M, Axelrod DA.   +13 more
europepmc   +2 more sources

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Therapies that activate the host immune system have shown tremendous promise for a variety of solid tumors. However, in most cancer types, fewer than half of patients respond to these immunotherapies.
Meredith L. Stone, Katherine B. Chiappinelli, Huili Li, Lauren Murphy, Meghan Travers, Michael J. Topper, Dimitrios Mathios, Michael Lim, Ie‐Ming Shih, Tian‐Li Wang, Chien‐Fu Hung, Vipul Bhargava, Karla R. Wiehagen, Glenn S. Cowley, Kurtis E. Bachman, Reiner Strick, Pamela L. Strissel, Stephen B. Baylin, Cynthia A. Zahnow   +18 more
openalex   +2 more sources

Regulatory T cells in kidney transplant recipients: the effect of induction immunosuppression therapy [PDF]

Nephrology, Dialysis and Transplantation, 2011
BACKGROUND Regulatory T cells have been suggested to down-regulate the alloimmune response. The aim of this prospective open study was to evaluate the effects of different inductive agents on peripheral blood regulatory T cells in kidney transplant ...
E. Krystufkova, Alena Sekerková, Ilja Střı́ž, I. Brabcova, Eva Girmanová, Ondřej Viklický   +5 more
openalex   +2 more sources

Successful recovery from severe COVID‐19 pneumonia after kidney transplantation: The interplay between immunosuppression and novel therapy including tocilizumab

Transplant Infectious Disease, 2020
Although immunosuppressed patients may be more prone to SARS‐CoV‐2 infection with atypical presentation, long‐term immunosuppression therapy may provide some sort of protection for severe clinical complications of COVID‐19.
Andrea Lauterio, M. Valsecchi, S Santambrogio, Riccardo De Carlis, Marco Merli, Angelo Calini, Leonardo Centonze, Vincenzo Buscemi, Maurizio Bottiroli, Massimo Puoti, Roberto Fumagalli, Luciano De Carlis   +11 more
openalex   +2 more sources

Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance sonodynamic therapy for immune activation

Theranostics, 2021
Background: Sonodynamic therapy (SDT) is a promising strategy to inhibit tumor growth and activate antitumor immune responses for immunotherapy. However, the hypoxic and immunosuppressive tumor microenvironment limits its therapeutic efficacy and ...
C. Ji, Jingxing Si, Yan Xu, Wenjing Zhang, Yaqian Yang, Xin He, H. Xu, X. Mou, Hao Ren, Hongqian Guo   +9 more
semanticscholar   +1 more source

Orthotopic Liver Transplantation of a SARS-CoV-2 Negative Recipient from a Positive Donor: The Border between Uncertainty and Necessity in a Pandemic Era- Case Report and Overview of the Literature

Medicina, 2023
(1) Introduction: Liver transplantation represents the gold-standard therapy in eligible patients with acute liver failure or end-stage liver disease.
Gabriela Droc, Cristina Martac, Cristina Georgiana Buzatu, Miruna Jipa, Maria Daniela Punga, Sebastian Isac   +5 more
doaj   +1 more source

Immunosuppressive Therapy in Myocarditis

Circulation Journal, 2014
Although there is general agreement on the favorable effect of immunosuppression in eosinophilic, granulomatous, giant-cell myocarditis and in lymphocytic myocarditis associated with connective tissue disorders and with rejection of a transplanted heart, its therapeutic role in lymphocytic inflammatory cardiomyopathy (ICM) is still debated.
FRUSTACI, ANDREA, CHIMENTI, CRISTINA
openaire   +7 more sources

COVID-19 as Another Trigger for HBV Reactivation: Clinical Case and Review of Literature

Pathogens, 2022
Universal hepatitis B virus (HBV) vaccination has been applied for years in most countries, but HBV infection remains an unresolved public health problem worldwide, with over one-third of the world’s population infected during their lifetime and ...
Caterina Sagnelli, Laura Montella, Pierantonio Grimaldi, Mariantonietta Pisaturo, Loredana Alessio, Stefania De Pascalis, Evangelista Sagnelli, Nicola Coppola   +7 more
doaj   +1 more source