Results 41 to 50 of about 269,737 (365)

Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]

, 2005
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K, Bond, GJ, Macedo, C, Mazariegos, GV, Murase, N, Peters, J, Reyes, J, Sindhi, R, Starzl, TE   +8 more
core   +1 more source

Perforator propeller flap for coverage of Achilles region defects caused by pyoderma gangrenosum

JPRAS Open, 2022
: Pyoderma gangrenosum (PG) is a rare neutrophilic inflammatory skin disease. Systemic corticosteroid and immunosuppressive agents are the mainstay treatment. PG usually precludes a surgical approach due to pathergy phenomenon.
Chun Wa Fong, Manuel Bento, Feng Jun Fang, Fong Kuong Pang, Io Hang Lio, Sut Sin Tong, Chou Kuan Hao   +6 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Current status of intestinal transplantation in children [PDF]

, 1998
Purpose: A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN ...
Asfar, Billingham, Casavilla, Deltz, Edward M Barksdale, Fontes, Furukawa, Garau, Goulet, Grant, Grant, Grant, Green, Hiro Furukawa, Iwaki, Javier Bueno, John J Fung, Jorge Reyes, Kareem Abu-Elmagd, Kashiwagi, Langnas, Lee, Lillehei, Manez, Margreiter, McAlister, Mike Green, Monchik, Murase, Murase, Porter, Putnam, Randhawa, Rao, Reyes, Reyes, Reyes, Samuel Kocoshis, Satoru Todo, Sharon Strom, Sigurdsson, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Takaya, Thomas E Starzl, Todo, Tzakis, White, William Irish   +52 more
core   +1 more source

Tacrolimus rescue therapy for renal allograft rejection - Five-year experience [PDF]

, 1997
Over the 5 year period from 7/14/1989 until 5/24/1994, we have attempted graft salvage with tacrolimus conversion in a total of 169 patients (median age 33 years, range 2-75 years) with ongoing rejection on baseline CsA immunosuppression after failure of
Demetris, AJ, Fung, JJ, Gritsch, HA, Jordan, ML, McCauley, J, McMichael, J, Naraghi, R, Randhawa, P, Scantlebury, VP, Shapiro, R, Smith, D, Starzl, TE, Vivas, CA   +12 more
core   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Analysis of early use of everolimus with low-dose calcineurin inhibitors in kidney transplant recipient

Вестник трансплантологии и искусственных органов, 2019
Aim: to evaluate the efficacy and safety of early use of everolimus in combination with a reduced dose of calcineurin inhibitors (CNI) after kidney transplantation and define approaches to the selection and management of patients on everolimus-based ...
I. G. Kim, N. A. Tomilina, I. V. Ostrovskaya, I. A. Skryabina, N. D. Fedorova   +4 more
doaj   +1 more source

Comparison of steroid-free immunosuppression and standard immunosuppression for liver transplant patients with hepatocellular carcinoma. [PDF]

PLoS ONE, 2013
Immunosuppression therapy following liver transplantation often includes steroids. However, extended corticosteroid therapy is associated with numerous complications.
Tonghai Xing, Li Huang, Zhenhai Yu, Lin Zhong, Shuyun Wang, Zhihai Peng   +5 more
doaj   +1 more source

Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]

, 2016
Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source