Results 11 to 20 of about 27,400 (237)

Recent advances in vaccine and immunotherapy for COVID-19 [PDF]

Human Vaccines & Immunotherapeutics, 2020
The COVID-19 pandemic caused by SARS-CoV-2 has resulted in millions of cases and hundreds of thousands of deaths. Beyond there being no available antiviral therapy, stimulating protective immunity by vaccines is the best option for managing future ...
Ali A. Rabaan, Shamsah H. Al-Ahmed, Ranjit Sah, Jaffar. A. Al-Tawfiq, Ayman M. Al-Qaaneh, Lamiaa H. Al-Jamea, Alexander Woodman, Manaf Al-Qahtani, Shafiul Haque, Harapan Harapan, D. Katterine Bonilla-Aldana, Pavan Kumar, Kuldeep Dhama, Alfonso J. Rodriguez-Morales   +13 more
doaj   +2 more sources

Clinical development of passive tau-based immunotherapeutics for treating primary and secondary tauopathies

, 2023
Introduction: Tauopathies are clinicopathological entities with increased and pathological deposition in glia and/or neurons of hyperphosphorylated aggregates of the microtubule-binding protein tau. In secondary tauopathies, i.e. Alzheimer’s disease (AD),
Cirillo N., Castellana F., Damiani C., Lampignano L., Lozupone M., Sardone R., Altamura M., Solfrizzi V., Bortone I., Bellomo A., Panza F., Zupo R., Stallone R., Dibello V., Daniele A.   +14 more
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Advances in Immunotherapeutics in Pancreatic Ductal Adenocarcinoma [PDF]

, 2023
Pancreatic ductal adenocarcinoma (PDAC) accounts for up to 95% of all pancreatic cancer cases and is the seventh-leading cause of cancer death. Poor prognosis is a result of late presentation, a lack of screening tests and the fact some patients develop ...
Merali, Nabeel, Maria-Danae Jessel, Frampton, Adam E., Annels, Nicola, Sivakumar, Shivan, Jessel, Maria-Danae, Nabeel Merali, Francesca Soraya La Costa, Chouari, Tarak, Tarak Chouari, Nicola Annels, Shivan Sivakumar, La Costa, Francesca Soraya, Adam E. Frampton   +13 more
core   +1 more source

Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences

Vaccines, 2016
Endosomal Toll-like receptors (TLR) such as TLR3, 7, 8 and 9 recognize pathogen associated nucleic acids. While DNA sequence does influence degree of binding to and activation of TLR9, it also appears to influence the ability of the ligand to reach the ...
Ghania Chikh, Rachel Luu, Shobhna Patel, Heather L. Davis, Risini D. Weeratna   +4 more
doaj   +1 more source

DNA‐based immunotherapeutics for the treatment of allergic disease

, 2001
Allergic diseases are a growing health concern in industrialized countries. Despite a number of effective therapeutic options for the prevention and treatment of the pathophysiologic responses which characterize allergic diseases, the induction of true ...
Raz, Eyal, Broide, David, Van Uden, John H., Horner, Anthony A., Zubeldia Ortuño, José Manuel   +4 more
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Immunotherapeutics in Multiple Myeloma: How Can Translational Mouse Models Help? [PDF]

, 2019
Multiple myeloma (MM) is usually diagnosed in older adults at the time of immunosenescence, a collection of age-related changes in the immune system that contribute to increased susceptibility to infection and cancer.
Ritchie, D, Koldej, R, Cooke, RE
core   +1 more source

Recent advances in toxoplasma gondii immunotherapeutics

, 2014
Toxoplasmosis is an opportunistic infection caused by the protozoan parasite Toxoplasma gondii. T gondii is widespread globally and causes severe diseases in individuals with impaired immune defences as well as congenitally infected infants.
Othman, R.Y., Lim, S.S.Y.
core   +2 more sources

Recent advancements in cancer immunotherapeutics [PDF]

, 2016
Cancer affects a wide range of organs and tissues within the body and epidemiologically is forecasted to affect almost half of the world's population. As an industry, cancer therapeutics represent a booming field.
Kim, Susie
core   +1 more source

Insights into Nanomedicine for Immunotherapeutics in Squamous Cell Carcinoma of the head and neck

, 2020
Xu Q, Fang M, Zhu J, et al. Insights into Nanomedicine for Immunotherapeutics in Squamous Cell Carcinoma of the head and neck. International Journal of Biological Sciences.
Qian, Xu, Leonard, Fransisca, Xu, Qiang, Fang, Meiyu, Yan, Lin, Sudhoff, Holger ; https://orcid.org/, Oppel, Felix, Dong, Haoru, Albers, Andreas E., Kaufmann, Andreas M., Zhu, Jing, Cao, Jun   +11 more
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Intravenously deliverable oncolytic virus VET3-TGI favorably alters the tumor microenvironment

Journal for ImmunoTherapy of Cancer
Background Oncolytic viruses have pledged to combat cancer by causing immunogenic cell death of cancerous cells while priming cancer-specific immune responses. These outcomes have proven elusive in the clinic.
Ming Zhang, Ravikumar Muthuswamy, Padma Sampath, Katy Barrett, Carly Carter, Gabriella Acosta-Barreto, Sydney Audino, Jirapach Moongdee, Rachel Bouchard, Deanna Dunstane, Nick Matteo, Kyle Biery, Evalien Duyvesteyn, Monica Cantos, Kimberly M Brothers, Dan Byrd, Taylor Dietrich, Stephen H Thorne   +17 more
doaj   +1 more source