Results 11 to 20 of about 156,654 (268)

Activation of cancer immunotherapy by nanomedicine

open access: yesFrontiers in Pharmacology, 2022
Cancer is one of the most difficult diseases to be treated in the world. Immunotherapy has made great strides in cancer treatment in recent years, and several tumor immunotherapy drugs have been approved by the U.S. Food and Drug Administration. Currently, immunotherapy faces many challenges, such as lacking specificity, cytotoxicity, drug resistance ...
Lijuan Wang   +5 more
openaire   +3 more sources

A STING-activating nanovaccine for cancer immunotherapy [PDF]

open access: yesNature Nanotechnology, 2017
The generation of tumour-specific T cells is critically important for cancer immunotherapy. A major challenge in achieving a robust T-cell response is the spatiotemporal orchestration of antigen cross-presentation in antigen-presenting cells with innate stimulation.
Min Luo   +15 more
openaire   +2 more sources

Pharmacological Activation of cGAS for Cancer Immunotherapy [PDF]

open access: yesFrontiers in Immunology, 2021
When compartmentally mislocalized within cells, nucleic acids can be exceptionally immunostimulatory and can even trigger the immune-mediated elimination of cancer. Specifically, the accumulation of double-stranded DNA in the cytosol can efficiently promote antitumor immunity by activating the cGAMP synthase (cGAS) / stimulator of interferon genes ...
Kyle M. Garland   +15 more
openaire   +3 more sources

Immunotherapy for B-cell lymphoma: current status and prospective advances

open access: yesFrontiers in Immunology, 2012
Therapy for non-Hodgkin's lymphoma has progressed significantly over the last decades. However, the majority of patients remain incurable, and novel therapies are needed.
Nurit eHollander
doaj   +1 more source

Impact of allergen immunotherapy after two years of suspension in patients with asthma

open access: yesRevista Alergia México, 2016
Background: Immunotherapy has proven to be effective in controlling allergic asthma. However, few studies have evaluated whether the control and reduction of drug treatment persist after treatment ends.
Jorge Sánchez   +2 more
doaj   +1 more source

Specific Active Immunotherapy for Melanoma

open access: yesAnnals of Surgery, 1979
The most effective immunization historically has been active immunization against a specific disease process. We report here the results of specific active immunization of 719 patients with invasive melanoma. The patients were sequentially immunized with approximately 2.5 × 107 x-irradiated, neuraminidase treated melanoma cells and BCG was used for its
H F, Seigler   +5 more
openaire   +3 more sources

Lymphocyte active immunotherapy for unexplained recurrent spontaneous abortion

open access: yesBangladesh Journal of Pharmacology, 2018
This study is to evaluate the curative effect of lymphocyte active immune treatment for unexplained recurrent spontaneous abortion. Fourteen randomized controlled trials of 994 subjects were included.
Xian Jiang Wei, Xiao Qin Fang, Ling Tong
doaj   +1 more source

Knowledge-map analysis of bladder cancer immunotherapy

open access: yesHuman Vaccines & Immunotherapeutics, 2023
This study aimed to conduct a bibliometric analysis in the field of bladder cancer (BC) immunotherapy, and explore the research trends, hotspots and frontiers from 2000 to 2022.
Zongwei Lv   +5 more
doaj   +1 more source

Active treatment for food allergy

open access: yesAllergology International, 2016
Food allergy has grown in rapidly in prevalence, currently affecting 5% of adults and 8% of children. Management strategy is currently limited to 1) food avoidance and 2) carrying and using rescue intramuscular epinephrine/adrenaline and oral ...
Aaron K. Kobernick, A. Wesley Burks
doaj   +1 more source

STING activation in cancer immunotherapy

open access: yesTheranostics, 2019
Cancer immunotherapy modulates and leverages the host immune system to treat cancer. The past decade has witnessed historical advancement of cancer immunotherapy. A myriad of approaches have been explored to elicit or augment anticancer innate immunity and/or adaptive immunity.
Su, Ting   +5 more
openaire   +2 more sources

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