Results 31 to 40 of about 234,058 (316)
A new approach in specific, active immunotherapy [PDF]
Cancer, 1977 A vaccinia virus-lysed autochthonous tumor cell vaccine (vaccinia oncolysate) is introduced as a new specific, active immunotherapeutic agent against human cancer. Mouse experiments showed the vaccine to be a safe and potent immune mechanism stimulator.
M K, Wallack +6 more
openaire +2 more sources
Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target. [PDF]
, 2018 Prostate cancer (PCa) is a leading cause of mortality and morbidity globally. While genomic alterations have been identified in PCa, in contrast to some other cancers, use of such information to personalize treatment is still in its infancy.
Dorff, Tanya +6 more
core +3 more sources
Light-activated nanomaterials for tumor immunotherapy
Frontiers in Chemistry, 2022 Tumor immunotherapy mainly relies on activating the immune system to achieve antitumor treatment. However, the present tumor immunotherapy used in the clinic showed low treatment efficacy with high systematic toxicity. To overcome the shortcomings of traditional drugs for immunotherapy, a series of antitumor immunotherapies based on nanomaterials have ...
Fang Wang +11 more
openaire +3 more sources
AllergoOncology: High innate IgE levels are decisive for the survival of cancer-bearing mice
World Allergy Organization Journal, 2019 Background: Atopics have a lower risk for malignancies, and IgE targeted to tumors is superior to IgG in fighting cancer. Whether IgE-mediated innate or adaptive immune surveillance can confer protection against tumors remains unclear.
Josef Singer +6 more
doaj +1 more source
Can Natural Products be Used to Overcome the Limitations of Colorectal Cancer Immunotherapy?
Frontiers in Oncology, 2022 Colorectal cancer (CRC) is a common cancer of the digestive system that endangers human health. Immunotherapy is widely used in the treatment of patients with cancer.
Jiahuan Dong +9 more
doaj +1 more source
The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]
, 2018 Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
core +2 more sources
Active immunotherapy for chronic diseases
Vaccine, 2013 With the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases.
Bachmann, M, Whitehead, P
openaire +4 more sources
Predictive biomarkers for checkpoint inhibitor-based immunotherapy: The Galectin-3 signature in NSCLCs [PDF]
, 2019 Checkpoint inhibitor-based immunotherapy is opening a promising scenario in oncology, with objective responses registered in multiple cancer types. However, reliable predictive markers of tumor responsiveness are still lacking.
Bartolazzi A. +4 more
core +1 more source
iScience, 2022 Summary: Immunotherapy shows durable response but only in a subset of patients, and test for predictive biomarkers requires procedures in addition to routine workflow.
Jiajun Deng +13 more
doaj +1 more source
Active immunotherapy for the treatment of cocaine dependence [PDF]
Drug News & Perspectives, 2010 Although cocaine is illegal in most countries of the world, addiction is common and increasing in many populations, and the effectiveness of current treatment options for those afflicted has been very limited. The availability of an anti-cocaine vaccine could offer help to those who wish to quit their addiction.
Berma M, Kinsey +2 more
openaire +2 more sources