Results 31 to 40 of about 231,111 (314)

Genopathomic profiling identifies signatures for immunotherapy response of lung adenocarcinoma via confounder-aware representation learning

open access: yesiScience, 2022
Summary: Immunotherapy shows durable response but only in a subset of patients, and test for predictive biomarkers requires procedures in addition to routine workflow.
Jiajun Deng   +13 more
doaj   +1 more source

What's new in the diagnosis and management of food allergy in children? [PDF]

open access: yes, 2013
This article reviews the recent advances in the diagnosis and management of IgE mediated food allergy in children. It will encompass the emerging technology of component testing; moves to standardization of the allergy food challenge; permissive diets ...
Campbell, DE, Turner, PJ
core   +1 more source

Activation of cancer immunotherapy by nanomedicine

open access: yesFrontiers in Pharmacology, 2022
Cancer is one of the most difficult diseases to be treated in the world. Immunotherapy has made great strides in cancer treatment in recent years, and several tumor immunotherapy drugs have been approved by the U.S. Food and Drug Administration. Currently, immunotherapy faces many challenges, such as lacking specificity, cytotoxicity, drug resistance ...
Lijuan Wang   +5 more
openaire   +3 more sources

Immunocompetent murine models for the study of glioblastoma immunotherapy. [PDF]

open access: yes, 2014
Glioblastoma remains a lethal diagnosis with a 5-year survival rate of less than 10%. (NEJM 352:987-96, 2005) Although immunotherapy-based approaches are capable of inducing detectable immune responses against tumor-specific antigens, improvements in ...
Bloch, Orin   +9 more
core   +2 more sources

STING activation in cancer immunotherapy

open access: yesTheranostics, 2019
Cancer immunotherapy modulates and leverages the host immune system to treat cancer. The past decade has witnessed historical advancement of cancer immunotherapy. A myriad of approaches have been explored to elicit or augment anticancer innate immunity and/or adaptive immunity.
Su, Ting   +5 more
openaire   +2 more sources

Active immunotherapy options for Alzheimer’s disease [PDF]

open access: yesAlzheimer's Research & Therapy, 2014
Alzheimer's disease (AD) is the most common cause of dementia and a major contributor to disability and dependency among older people. AD pathogenesis is associated with the accumulation of amyloid-beta protein (Aβ) and/or hyperphosphorylated tau protein in the brain. At present, current therapies provide temporary symptomatic benefit, but do not treat
Winblad, Bengt   +4 more
openaire   +2 more sources

The Application of iPSCs in Tumour Immunotherapy

open access: yesExpert Reviews in Molecular Medicine
Background Tumour immunotherapy holds great promise as a treatment for cancer, which ranks as the second highest cause of mortality worldwide. This therapeutic approach can be broadly categorized into two main types: active immunotherapy and passive or ...
Peinan Chen   +8 more
doaj   +1 more source

PET/CT imaging for tumour response assessment to immunotherapy: current status and future directions

open access: yesEuropean Radiology Experimental, 2020
Recent immunotherapeutic approaches have evolved as powerful treatment options with high anti-tumour responses involving the patient’s own immune system. Passive immunotherapy applies agents that enhance existing anti-tumour responses, such as antibodies
Marcus Unterrainer   +11 more
doaj   +1 more source

Ginsenosides: Allies of gastrointestinal tumor immunotherapy

open access: yesFrontiers in Pharmacology, 2022
In the past decade, immunotherapy has been the most promising treatment for gastrointestinal tumors. But the low response rate and drug resistance remain major concerns.
Yutao Feng   +6 more
doaj   +1 more source

Active immunotherapy for chronic diseases

open access: yesVaccine, 2013
With the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases.
Bachmann, M, Whitehead, P
openaire   +3 more sources

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