Results 111 to 120 of about 6,038 (211)

Cytotoxic activity of an anti-transferrin receptor immunotoxin on normal and leukemic human hematopoietic progenitors.

, 1991
The process of cellular iron uptake involves a specific receptor for the plasma carrier transferrin and a pathway of receptor-mediated endocytosis. Transferrin receptor expression is closely related to the rate of cell proliferation, and conjugates ...
CAZZOLA, MARIO, Rosti V, D'Uva R, Bergamaschi G, Ponchio L, Dezza L, Ascari E.   +6 more
core  

An epidermal growth factor receptor-targeting immunotoxin based on IgG shows potent antitumor activity against head and neck cancer

The epidermal growth factor receptor (EGFR) is an important target for cancer therapies. Many head and neck cancer (HNC) cells have been reported to overexpress EGFR; therefore, anti-EGFR therapies have been attempted in patients with HNC.
Yoo, TH, Lee, BS, Lee, YS, Ko, BJ, Ko, S, Kim, HJ, Park, D, Lee, Y, Park, J, Jung, ST, Kim, CH, Huang, M, Seo, J, Yang, YH   +13 more
core   +1 more source

Designing a Novel Immunotoxin against Prostate Cancer based on PE40 Toxin: An <i>In silico</i> Approach. [PDF]

Avicenna J Med Biotechnol
Azdoo S, Taheri-Anganeh M, Ahmadi K, Ghadimi Moghadam A, Movahedpour A, Jamshidi A.   +5 more
europepmc   +1 more source

Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. [PDF]

Front Immunol
Kozlíková M, Aukrust IKF, Rohlíčková M, Macháček M, Berg K, Weyergang A, Selbo PK.   +6 more
europepmc   +1 more source

A proimmunotoxin nanodrug targeting AIDS-associated non-Hodgkin lymphoma. [PDF]

J Control Release
Chen S, Qi T, Peng H, Kimura E, Zhang X, Kranz E, Cao Z, Wang Z, Chen W, Ancheta LR, Lappi DA, Chiou PY, Lu Y, Daniels-Wells TR, Penichet ML, Wen J.   +15 more
europepmc   +1 more source

USP40 protects podocytes by deubiquitylating integrin β1. [PDF]

Biochem Biophys Res Commun
Mikami N, Fukushima T, Takematsu H, Kiuchi Z, Fukuhara D, Tanaka E, Kimura T, Suehiro J, Fukutomi T, Kobayashi K, Pastan I, Nagata M, Takano T, Matsusaka T, Akimoto Y, Kawanishi K, Yan K.   +16 more
europepmc   +1 more source

CD64-directed immunotoxin inhibits arthritis in a novel CD64 transgenic rat model

, 2006
Macrophages are known to play a key role during inflammation in rheumatoid arthritis (RA). Inflammatory macrophages have increased expression of CD64, the high-affinity receptor for IgG.
van Vuuren, AJ, McLaughlin, PMJ, van Roon, JAG, Stuij, [No Value], Harmsen, MC, de Winkel, JGJV, Thepen, T, Harmsen, MC; id_orcid, Walraven, [No Value]   +8 more
core  

Enhanced Antitumor Efficacy of a Combination of Immunotoxin and Photosensitizer Under Illumination in Xenograft Mice. [PDF]

Biomedicines
Hamakubo S, Komatsu N, Kosai A, Kuroda M, Sawada M, Shimizu R, Ohashi R, Suenaga H, Hamakubo T, Abe T.   +9 more
europepmc   +1 more source

An Innovative Immunotoxin Design Against Allergy Based on the IL-33 Cytokine and the Ribotoxin α-Sarcin. [PDF]

Int J Mol Sci
Narbona J, Lázaro-Gorines R, Gutiérrez-Carmona A, López-Rodríguez JC, Villalba M, Lacadena J.   +5 more
europepmc   +1 more source

GPA33-Targeted Trimeric Immunotoxin Exhibits Enhanced Antitumor Activity in Human Colorectal Cancer Xenografts. [PDF]

Int J Mol Sci
Ruiz-de-la-Herrán J, Narbona J, Gordo RG, Sanz L, Lacadena J.   +4 more
europepmc   +1 more source