Results 111 to 120 of about 6,607 (210)

Cytotoxic activity of an anti-transferrin receptor immunotoxin on normal and leukemic human hematopoietic progenitors.

, 1991
The process of cellular iron uptake involves a specific receptor for the plasma carrier transferrin and a pathway of receptor-mediated endocytosis. Transferrin receptor expression is closely related to the rate of cell proliferation, and conjugates ...
CAZZOLA, MARIO, Rosti V, D'Uva R, Bergamaschi G, Ponchio L, Dezza L, Ascari E.   +6 more
core  

Immunotoxin WPD101a as a Potential Drug Candidate for Targeted Therapy in Muscle Invasive Bladder Cancer Expressing IL-13Rα2-In Vitro Study. [PDF]

Int J Mol Sci
Klimczak A, Krawczenko A, Stamnitz S, Bielawska-Pohl A, Piotrowska P, Grzelenska H, Wypychowska A, Kisielewicz A, Mielecki M, Borowski R, Olejniczak M, Pajak-Tarnacka B.   +11 more
europepmc   +1 more source

Novel PE-DT-fusion toxin enhances internalization and target-dependently restores the cytotoxicity of recombinant immunotoxins. [PDF]

Front Pharmacol
Fischer C, Wendland K, Ammon A, Gsottberger F, Mellenthin L, Petkovic S, Mackensen A, Müller F.   +7 more
europepmc   +1 more source

Development of a Targeted Choroidal Injury Model for the Study of Retinal Degenerations and Therapeutic Cell Replacement. [PDF]

Transl Vis Sci Technol
Pandala N, Haefeli LM, Lang M, Stone EM, Mullins RF, Tucker BA, Han IC.   +6 more
europepmc   +1 more source

Designing a Novel Immunotoxin against Prostate Cancer based on PE40 Toxin: An <i>In silico</i> Approach. [PDF]

Avicenna J Med Biotechnol
Azdoo S, Taheri-Anganeh M, Ahmadi K, Ghadimi Moghadam A, Movahedpour A, Jamshidi A.   +5 more
europepmc   +1 more source

In Silico Design and Structural Characterization of 4D5mocB-PE24: A Novel Immunotoxin for EpCAM-Targeted Cancer Therapy

Introduction: Antibody-based immunotoxins are a promising novel therapeutic approach aimed at targeted cancer therapy, utilizing the target specificity of antibody fragments attached to a potent cytotoxic ...
Safar Farajnia, Leila Rahbarnia, Reza Salahlou, Hossein Babaei, Fatemeh Heidari   +4 more
core   +1 more source

Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. [PDF]

Front Immunol
Kozlíková M, Aukrust IKF, Rohlíčková M, Macháček M, Berg K, Weyergang A, Selbo PK.   +6 more
europepmc   +1 more source

Podocyte injury damages podocytes in chimeric organoids. [PDF]

PLoS One
Udagawa T, Araoka T, Osafune K, Matsusaka T.   +3 more
europepmc   +1 more source

A proimmunotoxin nanodrug targeting AIDS-associated non-Hodgkin lymphoma. [PDF]

J Control Release
Chen S, Qi T, Peng H, Kimura E, Zhang X, Kranz E, Cao Z, Wang Z, Chen W, Ancheta LR, Lappi DA, Chiou PY, Lu Y, Daniels-Wells TR, Penichet ML, Wen J.   +15 more
europepmc   +1 more source

Correction: Antibody-drug conjugates in cancer therapy: current advances and prospects for breakthroughs. [PDF]

Front Cell Dev Biol
Wu D, Yang K, He R, Yin R, Shui L.
europepmc   +1 more source