Results 101 to 110 of about 6,607 (210)

Clinical Development of Experimental Therapies for Malignant Glioma

Sultan Qaboos University Medical Journal, 2011
Advances in medical and surgical treatments in the last two to three decades have resulted in quantum leaps in the overall survival of patients with many types of non-central nervous system (CNS) malignant disease, while survival of patients with ...
Nikolai G Rainov, Volkmar Heidecke
doaj  

Supplementary Methods, Supplementary Figures 1-5, and Supplementary Tables 1-2 from Targeted Cytolysins Synergistically Potentiate Cytoplasmic Delivery of Gelonin Immunotoxin

, 2013
PDF file- 129 KB, Supplementary Methods; Supplementary Figure S1: Potentiator binding and cytotoxicity; Supplementary Figure S2: Potentiator hemolytic activity; Supplementary Figure S3: Potentiation of gelonin immunotoxin cytotoxicity; Supplementary ...
K. Dane Wittrup (1294554), Christopher M. Pirie (15066897), David V. Liu (1593601)   +2 more
core   +1 more source

Data for Mechanism of Triterpenoid Saponin Mediated Augmentation of Saporin Based Immunotoxin Cytotoxicity

Dataset for the thesis: Mechanism of Triterpenoid Saponin Mediated Augmentation of Saporin Based Immunotoxin ...
Flavell, David J., Wensley, Harrison, James   +1 more
core   +1 more source

Computational Design and Evaluation of scFv-DSH2a as a PSMA-Targeted Immunotoxin for Prostate Cancer Therapy: Computational design of scFv-DSH2a as a PSMA-targeted immunotoxin

Prostate cancer is one of the most prevalent malignancies in men and a leading cause of cancer-related mortality. The prostate-specific membrane antigen (PSMA), which is highly overexpressed in prostate tumors and internalized upon ligand binding ...
Mousavipour, Sara, Mousavi-Niri, Neda
core   +1 more source

Immunotoxin-mediated targeting of claudin-4 inhibits the proliferation of cancer cells

, 2013
Immunotoxins are engineered chimeric proteins that consist of a fragment of a toxin fused to a modified antibody or growth factor capable of targeting specific cells.
Wei, MQ, Alqurashi, N, Ipe, DS, Hashimi, SM, Yu, S   +4 more
core   +1 more source

Induction and increase of HLA-DR antigen expression by immune interferon on ML-3 cell line enhances the anti-HLA-DR immunotoxin activity

, 1990
SUMMARY In order to evaluate the impact of induction and increase target antigen expression on immunotoxin potency, we measured the potentiating effect of recombinant immune interferon-gamma (rIFN-γ) on the cytotoxicity of an anti HLA-DR ...
C BORDIER, F ROUBINET, M BRANDELY, G LAURENT, J P JAFFREZOU, C XAVIER, P CARAYON, M CHIRON   +7 more
core   +1 more source

Development of an immunotoxin incorporating the Australian jumper ant toxin, pilosulin 1 [PDF]

, 2007
University of Technology, Sydney. Faculty of Science.Immunotoxins are therapeutic agents that directly target toxins to specific cells and are generally comprised of an antibody or antibody fragment (Fab or scFv) linked to a toxic moiety.
Lemke, Susan Jane
core  

Supplementary Figure 2 from Efficacy of RG7787, a Next-Generation Mesothelin-Targeted Immunotoxin, against Triple-Negative Breast and Gastric Cancers

, 2014
Supplementary Figure 2.
Gerhard Niederfellner (107798), Laiman Xiang (14982983), Christine Alewine (614463), Klaus Bosslet (3021141), Takao Yamori (704541), Ira Pastan (303807)   +5 more
core   +1 more source

immunotoxin

Citation: 'immunotoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13326 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

An epidermal growth factor receptor-targeting immunotoxin based on IgG shows potent antitumor activity against head and neck cancer

The epidermal growth factor receptor (EGFR) is an important target for cancer therapies. Many head and neck cancer (HNC) cells have been reported to overexpress EGFR; therefore, anti-EGFR therapies have been attempted in patients with HNC.
Yoo, TH, Lee, BS, Lee, YS, Ko, BJ, Ko, S, Kim, HJ, Park, D, Lee, Y, Park, J, Jung, ST, Kim, CH, Huang, M, Seo, J, Yang, YH   +13 more
core   +1 more source