Results 81 to 90 of about 9,896 (218)
Exploring the Role of Acrylamide in Food Allergy via Dendritic Cell‐Dependent Th2 Immune Responses
Food Frontiers, Volume 7, Issue 1, January 2026.Acrylamide may disrupt immune tolerance as a foodborne immunotoxicant, priming allergic inflammatory susceptibility through DC‐dependent Th2/Th17 polarization, TLR4/NF‐κB signaling amplification, and IL‐10 production suppression. ABSTRACT Acrylamide (AA), a prevalent food processing contaminant with recognized multi‐organ toxicity, has an unexplored ...
Xue Feng +8 more
wiley +1 more source
Immunotoxins: Targeted Toxin Delivery for Cancer Therapy
Pharmaceutical Fronts, 2019 Immunotoxins are proteins that consist of a protein toxin conjugated to a specific targeting moiety. The targeting moiety is usually an antibody or ligand, such as monoclonal antibody, antibody fragment, a cytokine, or a growth factor. The toxins usually
Xin Mei +3 more
doaj +1 more source
Food Safety and Health, Volume 4, Issue 1, Page 67-81, January 2026.Aflatoxins, carcinogenic compounds in milk; reduction strategies such as thermal deactivation, UV light exposure, ionizing radiation, and solvent extraction. ABSTRACT Aflatoxins (AFs) are known to be cancer causing substances recognized within milk along with the milk goods.
Akshay Ramani +6 more
wiley +1 more source
Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells [PDF]
, 2016 Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human
Binz, T. +3 more
core +1 more source
Global Challenges, Volume 10, Issue 1, January 2026.Probing and sustaining the health of Earth's ecosystems and their inhabitants requires convergent approaches at multiple length and time scales. Predictive computational and physical modeling, together with novel biotechnologies applied in unexpected ways, are paving the way for discoveries at the intersection of epidemiology and geospatial science ...
Eric J. Anderson +6 more
wiley +1 more source
Journal of Biomechanical Science and Engineering, 2011 The purpose of this research is to develop minimally invasive medical devices by applying heated actuations of Shape Memory Alloy (SMA) transducers using a medical Ti-Ni alloy in order to enable minimal hypodermic invasive microvolume for either blood ...
Hidetake YAMAMOTO
doaj +1 more source
Toxins, 2020 Toxins, while harmful and potentially lethal, have been engineered to develop potent therapeutics including cytotoxins and immunotoxins (ITs), which are modalities with highly selective targeting capabilities.
Shusei Hamamichi +2 more
doaj +1 more source
Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps
Journal of Applied Toxicology, Volume 46, Issue 1, Page 61-77, January 2026.ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira +10 more
wiley +1 more source
Toxins, 2017 Immunotoxins (ITs) are hybrid proteins combining the binding specificity of antibodies with the cytocidal properties of toxins. They represent a promising approach to lymphoma therapy. The cytotoxicity of two immunotoxins obtained by chemical conjugation
Letizia Polito +6 more
doaj +1 more source
Targeting Receptors on Cancer Cells with Protein Toxins
Biomolecules, 2020 Cancer cells frequently upregulate surface receptors that promote growth and survival. These receptors constitute valid targets for intervention. One strategy involves the delivery of toxic payloads with the goal of killing those cancer cells with high ...
Antonella Antignani +5 more
doaj +1 more source