Results 241 to 250 of about 170,756 (308)

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

In silico design and evaluation of a multiepitope vaccine against Bordetella pertussis: structural, immunological, and biological properties. [PDF]

Genomics Inform
Souod N, Madanchi H, Bahrami F, Pakzad SR, Shahcheraghi F, Ajdary S.   +5 more
europepmc   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

In silico design of Ebola virus Glycoprotein antigenic peptides as vaccine candidates. [PDF]

PLoS One
Lara-Ramírez D, Santacruz-Tinoco CE, Ramón-Gallegos E, Muñoz-Medina JE.   +3 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Identification of Novel HPK1 Hit Inhibitors: From In Silico Design to In Vitro Validation. [PDF]

Int J Mol Sci
Isawi IH, Obeidat RM, Alnabulsi S, Al Zoubi R.   +3 more
europepmc   +1 more source

Animal research in the UK: Regulation, implementation, welfare and development of new approach methodologies

Animal Models and Experimental Medicine, EarlyView.
Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith, James Bussell, Maggie Gentry, Elliot Lilley, Cathy Merry, Judy MacArthur Clark, William Reynolds   +6 more
wiley   +1 more source

In silico design of novel multi-epitope peptide vaccine against Neospora caninum induced cattle abortion targeting extracellular GRA2 and Nc-p43 protein. [PDF]

Sci Rep
Mashrur MN, Imranuzzaman M, Barua H, Hasan MR, Hridy FK, Sakib TS, Rani NA, Rahman M, Ahsan G, Ashraf T, Muktadir S, Belal AB, Roy A, Mohiuddin ASM, Shishir TA, Hossain H, Rahman MM, Akhand MRN, Rahman MM.   +18 more
europepmc   +1 more source

Retraction: In Silico design of a multi-epitope vaccine for Human Parechovirus: Integrating immunoinformatics and computational techniques. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

DNAdesign: feature-aware in silico design of synthetic DNA through mutation. [PDF]

Bioinformatics
Wang Y, Li J, Chiu TP, Gompel N, Rohs R.
europepmc   +1 more source