Results 1 to 10 of about 32,158 (205)

Unlocking Antimicrobial Peptides: In Silico Proteolysis and Artificial Intelligence-Driven Discovery from Cnidarian Omics. [PDF]

Molecules
Overcoming the growing challenge of antimicrobial resistance (AMR), which affects millions of people worldwide, has driven attention for the exploration of marine-derived antimicrobial peptides (AMPs) for innovative solutions. Cnidarians, such as corals,
Barroso RA, Agüero-Chapin G, Sousa R, Marrero-Ponce Y, Antunes A.   +4 more
europepmc   +4 more sources

In silico proteolysis and analysis of bioactive peptides from sequences of fatty acid desaturase 3 (FAD3) of flaxseed protein. [PDF]

Saudi J Biol Sci, 2021
Flaxseed (Linum usitatissimum), commonly known as linseed is an oilseed crop, emerging as an important and functional ingredient of food and has been paid more attention due to its nutritional value as well as beneficial effects. It is mainly rich in is α-linolenic acid (ALA, omega-3 fatty acid), fibres and lignans that have potential health benefits ...
Langyan S, Khan FN, Yadava P, Alhazmi A, Mahmoud SF, Saleh DI, Zuan ATK, Kumar A.   +7 more
europepmc   +3 more sources

Novel dipeptidyl peptidase-IV and angiotensin-I-converting enzyme inhibitory peptides released from quinoa protein by in silico proteolysis. [PDF]

Food Sci Nutr, 2020
AbstractQuinoa protein has been paid more and more attention because of its nutritional properties and beneficial effects. With the development of bioinformatics, bioactive peptide database and computer‐assisted simulation provide an efficient and time‐saving method for the theoretical estimation of potential bioactivities of protein.
Guo H, Richel A, Hao Y, Fan X, Everaert N, Yang X, Ren G.   +6 more
europepmc   +5 more sources

Discovery of Anti-Hypertensive Oligopeptides from Adlay Based on In Silico Proteolysis and Virtual Screening. [PDF]

Int J Mol Sci, 2016
Adlay (Coix larchryma-jobi L.) was the commonly used Traditional Chinese Medicine (TCM) with high content of seed storage protein. The hydrolyzed bioactive oligopeptides of adlay have been proven to be anti-hypertensive effective components. However, the structures and anti-hypertensive mechanism of bioactive oligopeptides from adlay were not clear. To
Qiao L, Li B, Chen Y, Li L, Chen X, Wang L, Lu F, Luo G, Li G, Zhang Y.   +9 more
europepmc   +4 more sources

A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin. [PDF]

Molecules
The prediction of polypeptide chain fragmentation during digestion (proteolysis) of protein substrates by trypsin was carried out for globular β-lactoglobulin (β-LG) and micellar β-casein (β-CN).
Vorob'ev MM.
europepmc   +2 more sources

Potential Biological Activities of Peptides Generated during Casein Proteolysis by Curly Kale (Brassica oleracea L. var. sabellica L.) Leaf Extract: An In Silico Preliminary Study [PDF]

Foods, 2021
This study is a brief report on the proteolytic activity of curly kale leaf extract against casein. Casein degradation products and an in silico analysis of the biological activity of the peptides obtained was performed.
Magdalena Polak-Berecka, Magdalena Michalak-Tomczyk, Katarzyna Skrzypczak, Katarzyna Michalak, Kamila Rachwał, Adam Waśko   +5 more
doaj   +3 more sources

Identification of Novel Umami Peptides from Yak Bone Collagen and Mechanism Exploration Through <i>In Silico</i> Discovery, Molecular Docking, and Electronic Tongue. [PDF]

Foods
Umami peptides were screened and identified from yak bone collagen for the first time by in silico analysis, molecular docking, and electronic tongue.
Mei Y, Wu X, Xie R, Wu Y, Du H, Chen W, Hu J, Zhao K, Guo R, Zhang J.   +9 more
europepmc   +2 more sources

Plant-Derived Proteins and Peptides as Potential Immunomodulators

Molecules, 2023
The immune response of humans may be modulated by certain biopeptides. The present study aimed to determine the immunomodulatory potential of plant-derived food proteins and hydrolysates obtained from these proteins via monocatalytic in silico hydrolysis
Iwona Szerszunowicz, Szymon Kozicki
doaj   +1 more source

In Silico Approach of Glycinin and Conglycinin Chains of Soybean By-Product (Okara) Using Papain and Bromelain

Molecules, 2022
This study explores utilization of a sustainable soybean by-product (okara) based on in silico approach. In silico approaches, as well as the BIOPEP database, PeptideRanker database, Peptide Calculator database (Pepcalc), ToxinPred database, and AllerTop
Andriati Ningrum, Dian Wahyu Wardani, Nurul Vanidia, Achmat Sarifudin, Rima Kumalasari, Riyanti Ekafitri, Dita Kristanti, Woro Setiaboma, Heli Siti Halimatul Munawaroh   +8 more
doaj   +1 more source

Exploring the Potential of Black Soldier Fly Larval Proteins as Bioactive Peptide Sources through in Silico Gastrointestinal Proteolysis: A Cheminformatic Investigation

Catalysts, 2023
Despite their potential as a protein source for human consumption, the health benefits of black soldier fly larvae (BSFL) proteins following human gastrointestinal (GI) digestion are poorly understood. This computational study explored the potential of BSFL proteins to release health-promoting peptides after human GI digestion. Twenty-six proteins were
Fai-Chu Wong, You-Han Lee, Joe-Hui Ong, Fazilah Abd Manan, Mohamad Zulkeflee Sabri, Tsun-Thai Chai   +5 more
openaire   +3 more sources