Results 51 to 60 of about 117,925,879 (224)
Identification of Allergenic Tropomyosins with Known and Unknown Sequences in Seafood Products
Applied SciencesInvertebrate tropomyosins belong to the key food allergens. Several peptides likely to be released during proteolysis can be found in many sequences of proteins from this family. The aim of the present study was to evaluate the possibility of identifying
Marta Godlewska +3 more
doaj +1 more source
in-silico-uce-probes-to-contigs.lastz.tar.gz
, 2014 LASTZ files showing mapping of UCE probes onto in silico genome slices AND probe.matches.sqlite ...
Brant C. Faircloth (143432) +7 more
core +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
IP Indian Journal of Clinical and Experimental DermatologySkin diseases represent a significant burden on global healthcare systems, with protein deposition playing a pivotal role in their pathogenesis, including conditions such as macular amyloidosis. This study aimed to assess the proteolytic activity of the enzyme Papain on deposited protein, offering insights into potential therapeutic strategies.
Vrushali Neve +4 more
openaire +1 more source
Molecules, 2023 Proteolysis-Targeting Chimeras (PROTACs) have recently emerged as a promising technology in the drug discovery landscape. Large interest in the degradation of the androgen receptor (AR) as a new anti-prostatic cancer strategy has resulted in several ...
Giulia Apprato +4 more
doaj +1 more source
Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Extracellular peptidase hunting for improvement of protein production in plant cells and roots
Frontiers in Plant Science, 2015 Plant-based recombinant protein production systems have gained an extensive interest over the past few years, because of their reduced cost and relative safety. Although the first products are now reaching the market, progress are still needed to improve
Jérôme eLallemand +11 more
doaj +1 more source
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
Advanced Science, EarlyView.A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
wiley +1 more source
Insights on a putative aminoacyl-tRNA-protein transferase of Leishmania major. [PDF]
PLoS ONE, 2018 The N-end rule pathway leads to regulated proteolysis as an adaptive response to external stress and is ubiquitous from bacteria to mammals. In this study, we investigated a gene coding for a putative core enzyme of this post-translational regulatory ...
Rohit Sharma +6 more
doaj +1 more source
in-silico-taxon-set-alignment-data.tar.gz
, 2014 Archive file containing nested directories of in-silico alignment and analysis data.
Brant C. Faircloth (143432) +7 more
core +1 more source