Results 41 to 50 of about 120,404,711 (181)

Absorption of Hydroxyproline-Containing Peptides in Vascularly Perfused Rat Small Intestinein Situ

Bioscience, Biotechnology, and Biochemistry, 2009
To assess the digestion and assimilation of gelatin and gelatin hydrolysates, the in situ absorption of typical hydroxyproline-containing dipeptides, Pro-Hyp, Hyp-Gly, Ser-Hyp Ala-Hyp, and pentadecapeptide, (Pro-Hyp-Gly)(5), was investigated in the rat small intestine.
LIU, Chinfang, SUGITA, Kazuko, NIHEI, Ken-ichi, YONEYAMA, Koichi, TANAKA, Hideyuki   +4 more
openaire   +2 more sources

Engineered small intestinal system as an alternative to in-situ intestinal permeability model

, 2018
Intestinal permeability is the most important factor that determines the bioavailability. In-vitro techniques like Caco-2 model and Ussing chamber are used for evaluating the intestinal permeability of the bioactive compound.
S. Parthasarathi, C. Anandharamakrishnan, Anu Bhushani, J., J. Anu Bhushani, Parthasarathi, S., Anandharamakrishnan, C.   +5 more
core   +1 more source

The Absorption Characteristics of Nonvolatile Components in a Water Extraction From Amomi fructus as Determined by In Situ Single-Pass Intestinal Perfusion and High-Performance Liquid Chromatography

Frontiers in Pharmacology, 2020
BackgroundAmomi fructus is a famous traditional Chinese medicine (TCM) that can exert beneficial effects during the treatment of gastrointestinal diseases and is used widely in China and other countries in Southeast Asia.
Yuebao Yao, Wenjuan Mi, Guangzhao Cao, Ruiqi Yang, Huirong Chen, Yong Liu, Huiqin Zou, Yonghong Yan   +7 more
doaj   +1 more source

The in-situ absorption of antipyrine as a measure of intestinal blood flow in Fluosol-DA haemodiluted rats

, 1990
The effect of moderate Fluosol-DA haemodilution on intestinal blood flow has been investigated in the rat. Antipyrine in-situ intestinal absorption is blood flow limited, and did not alter 0.5, 24, 48, or 72 h after haemodilution with 40 mL kg−1 Fluosol.
Lisa G White, Robert P Shrewsbury
core   +1 more source

The absorption of oral morroniside in rats: In vivo, in situ and in vitro studies

Acta Pharmaceutica, 2019
Morroniside is one of the most important iridoid glycosides from Cornus officinalis Sieb. et Zucc. In the present study, the pharmacokinetics and bioavailability studies of morroniside were conducted on Sprague-Dawley (SD) rats.
Xiong Shan, Li Jinglai, Mu Yanling, Zhang Zhenqing   +3 more
doaj   +1 more source

Efeitos hemodinâmicos e metabólicos iniciais da perfusão hipotérmica intestinal in situ.: avaliação de um novo modelo canino de autotransplante intestinal Initial hemodynamic and metabolic effects of intestinal hypothermic perfusion in situ: an alternative model of canine intestinal autotransplantation

Acta Cirúrgica Brasileira, 2004
O transplante intestinal tem sido utilizado como uma alternativa promissora no tratamento da síndrome do intestino curto em pacientes adultos e pediátricos.
Ruy Jorge Cruz Junior, Cristiano de Jesus Correia, Luiz Francisco Poli de Figueiredo, Maurício Rocha e Silva   +3 more
doaj   +1 more source

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]

, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Pulimood, AB, Rook, GWA, Peter, S, Donoghue, HD   +3 more
core  

Glyceroniosomes for enhanced intestinal absorption of hydrochlorothiazide and lisinopril in their fixed dose combination

Scientific Reports
The objective was to investigate the effect of co-administration of hydrochlorothiazide and lisinopril as fixed dose combination on their intestinal absorption. The scope was extended to enhance intestinal absorption of both drugs.
Aya R. Elbasuony, Abdelaziz E. Abdelaziz, Eman A. Mazyed, Gamal M. El Maghraby   +3 more
doaj   +1 more source

Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies [PDF]

, 2015
The aim of this study was to evaluate the intestinal disposition of abiraterone acetate, an ester prodrug of the anticancer agent abiraterone. Stability of the prodrug and solubility and dissolution characteristics of both abiraterone and abiraterone ...
Brouwers, Joachim, Annaert, Pieter, Geboers, Sophie, Snoeys, Jan, Stappaerts, Jef, Tack, Jan, Augustijns, Patrick   +6 more
core   +1 more source

Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats

Pharmaceutics, 2020
An increased interest in colonic drug delivery has led to a higher focus on the design of delivery devices targeting this part of the gastrointestinal tract. Microcontainers have previously facilitated an increase in oral bioavailability of drugs.
Juliane Fjelrad Christfort, Antonio José Guillot, Ana Melero, Lasse Højlund Eklund Thamdrup, Teresa M. Garrigues, Anja Boisen, Kinga Zór, Line Hagner Nielsen   +7 more
doaj   +1 more source