Results 41 to 50 of about 8,658,473 (396)
The Importance of Mechanical Forces for in vitro Endothelial Cell Biology
Blood and lymphatic vessels are lined by endothelial cells which constantly interact with their luminal and abluminal extracellular environments. These interactions confer physical forces on the endothelium, such as shear stress, stretch and stiffness ...
E. Gordon, L. Schimmel, Maike Frye
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation).
Kirsty Meldrum+4 more
doaj +1 more source
Background Diagnosing ventilator-associated pneumonia (VAP) in an intensive care unit (ICU) is a complex process. Our aim was to collect, evaluate and represent the information relating to current clinical practice for the diagnosis of VAP in UK NHS ICUs,
W. S. Jones+11 more
doaj +1 more source
From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights
Although most same-stage non-alcoholic fatty liver disease (NAFLD) patients exhibit similar histologic sequelae, the underlying mechanisms appear to be highly heterogeneous.
Alexandra Gatzios+7 more
doaj +1 more source
In vitro regeneration and conservation of Indigo (Indigofera tinctoria L.) by slow growth induction [PDF]
An efficient protocol for rapid in vitro clonal propagation has been established. Shoot proliferation was obtained from nodal explants in Murashige and Skoog medium supplemented with 1.0 mg L-1BA and 0.1 mg L-1 IAA.
B, S. K. (Soni)+3 more
core +1 more source
Cell Culture Based in vitro Test Systems for Anticancer Drug Screening
The development of new high-tech systems for screening anticancer drugs is one of the main problems of preclinical screening. Poor correlation between preclinical in vitro and in vivo data with clinical trials remains a major concern.
K. Kitaeva+3 more
semanticscholar +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
In order to identify biomarkers for earlier prediction of COVID-19 outcome, we collected blood samples from patients with fatal outcomes (non-survivors) and with positive clinical outcomes (survivors) at ICU admission and after seven days.
Simone Kattner+8 more
doaj +1 more source
In Vitro Fertility of Post-thawed Epididymal Ram Spermatozoa After Storage at 5 °C Before Cryopreservation [PDF]
This study addressed the effects of storage duration of epididymides at 5 °C before sperm collection and their fertility after cryopreservation in vitro.
fahrudin, M. (M)+2 more
core