Results 41 to 50 of about 7,982,325 (356)
mAbs, 2021 Bispecific antibodies can uniquely influence cellular responses, but selecting target combinations for optimal functional activity remains challenging.
Pallavi Bhatta +12 more
doaj +1 more source
Magnetic biophysical characterization of biomimetic polyeth-ylenimine-coated nanoparticles on in vitro silico model [PDF]
arXiv, 2022 Understanding the biophysical and magnetic interactions of nanoparticles (NPs) with cell mem-branes is critical for developing effective nanocarrier systems for drug delivery applications and targeted nanophysics applications. Recent discoveries in nanomedicine can be used to test an in vitro system that reproduce a similar tumor model.
arxiv
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Diagnostic and Prognostic Research, 2022 Background Diagnosing ventilator-associated pneumonia (VAP) in an intensive care unit (ICU) is a complex process. Our aim was to collect, evaluate and represent the information relating to current clinical practice for the diagnosis of VAP in UK NHS ICUs,
W. S. Jones +11 more
doaj +1 more source
A survey on Organoid Image Analysis Platforms [PDF]
arXiv, 2023 An in-vitro cell culture system is used for biological discoveries and hypothesis-driven research on a particular cell type to understand mechanistic or test pharmaceutical drugs. Conventional in-vitro cultures have been applied to primary cells and immortalised cell lines plated on 2D surfaces.
arxiv
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Scientific Reports, 2023 In order to identify biomarkers for earlier prediction of COVID-19 outcome, we collected blood samples from patients with fatal outcomes (non-survivors) and with positive clinical outcomes (survivors) at ICU admission and after seven days.
Simone Kattner +8 more
doaj +1 more source
From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights
Biomedicines, 2022 Although most same-stage non-alcoholic fatty liver disease (NAFLD) patients exhibit similar histologic sequelae, the underlying mechanisms appear to be highly heterogeneous.
Alexandra Gatzios +7 more
doaj +1 more source
Transfer Learning from Synthetic In-vitro Soybean Pods Dataset for In-situ Segmentation of On-branch Soybean Pod [PDF]
arXiv, 2022 The mature soybean plants are of complex architecture with pods frequently touching each other, posing a challenge for in-situ segmentation of on-branch soybean pods. Deep learning-based methods can achieve accurate training and strong generalization capabilities, but it demands massive labeled data, which is often a limitation, especially for ...
arxiv
Performance of In Vitro Cassava (Manihot esculenta Crantz) Plantlets Weaned with Locally Sourced Substrates [PDF]
, 2018 The performance of in vitro cassava plantlets weaned on different locally sourced substrates was evaluated. Nodal cuttings were excised from healthy six weeks old OG 001cassava variety in the culture room of tissue culture laboratory of National Root ...
Iwuagwu, M. O. (Mary) +1 more
core +1 more source