Results 41 to 50 of about 8,658,473 (396)

The Importance of Mechanical Forces for in vitro Endothelial Cell Biology

open access: yesFrontiers in Physiology, 2020
Blood and lymphatic vessels are lined by endothelial cells which constantly interact with their luminal and abluminal extracellular environments. These interactions confer physical forces on the endothelium, such as shear stress, stretch and stiffness ...
E. Gordon, L. Schimmel, Maike Frye
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Determining the toxicological effects of indoor air pollution on both a healthy and an inflammatory-comprised model of the alveolar epithelial barrier in vitro

open access: yesParticle and Fibre Toxicology
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation).
Kirsty Meldrum   +4 more
doaj   +1 more source

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology

open access: yesDiagnostic and Prognostic Research, 2022
Background Diagnosing ventilator-associated pneumonia (VAP) in an intensive care unit (ICU) is a complex process. Our aim was to collect, evaluate and represent the information relating to current clinical practice for the diagnosis of VAP in UK NHS ICUs,
W. S. Jones   +11 more
doaj   +1 more source

From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights

open access: yesBiomedicines, 2022
Although most same-stage non-alcoholic fatty liver disease (NAFLD) patients exhibit similar histologic sequelae, the underlying mechanisms appear to be highly heterogeneous.
Alexandra Gatzios   +7 more
doaj   +1 more source

In vitro regeneration and conservation of Indigo (Indigofera tinctoria L.) by slow growth induction [PDF]

open access: yes, 2016
An efficient protocol for rapid in vitro clonal propagation has been established. Shoot proliferation was obtained from nodal explants in Murashige and Skoog medium supplemented with 1.0 mg L-1BA and 0.1 mg L-1 IAA.
B, S. K. (Soni)   +3 more
core   +1 more source

Cell Culture Based in vitro Test Systems for Anticancer Drug Screening

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The development of new high-tech systems for screening anticancer drugs is one of the main problems of preclinical screening. Poor correlation between preclinical in vitro and in vivo data with clinical trials remains a major concern.
K. Kitaeva   +3 more
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Identification of two early blood biomarkers ACHE and CLEC12A for improved risk stratification of critically ill COVID-19 patients

open access: yesScientific Reports, 2023
In order to identify biomarkers for earlier prediction of COVID-19 outcome, we collected blood samples from patients with fatal outcomes (non-survivors) and with positive clinical outcomes (survivors) at ICU admission and after seven days.
Simone Kattner   +8 more
doaj   +1 more source

In Vitro Fertility of Post-thawed Epididymal Ram Spermatozoa After Storage at 5 °C Before Cryopreservation [PDF]

open access: yes, 2013
This study addressed the effects of storage duration of epididymides at 5 °C before sperm collection and their fertility after cryopreservation in vitro.
fahrudin, M. (M)   +2 more
core  

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