Results 41 to 50 of about 8,721,497 (397)

Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries

mAbs, 2021
Bispecific antibodies can uniquely influence cellular responses, but selecting target combinations for optimal functional activity remains challenging.
Pallavi Bhatta, Kevin D. Whale, Amy K. Sawtell, Clare L. Thompson, Stephen E. Rapecki, David A. Cook, Breda M. Twomey, Milena Mennecozzi, Laura E. Starkie, Emily M. C. Barry, Shirley J. Peters, Ahmad M. Kamal, Helene M. Finney   +12 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Fermentation Quality and in Vitro Nutrient Digestibility of Fresh Rice Straw-Based Silage Treated with Lactic Acid Bacteria [PDF]

, 2014
The aim of the experiment was to evaluate fermentation characteristics and in vitro nutrient digestibility of fresh rice straw-based silage ensiled with addition of epiphytic lactic acid bacteria (LAB) inoculant.
Hariadi, B. T. (B), Sabariah, V. (V), Santoso, B. (B), Sraun, T. (T)   +3 more
core  

Proximate analysis and in-vitro gas production of predominant forages in Afe Babalola University rangeland as feed resources for ruminant production [PDF]

, 2017
In Nigeria, the major feed resource for ruminant production is the natural grazeland. However, most forage found on such lands cannot absolutely support ruminant production.
Bamigboye, F. O. (F), Oluwarinde, O. (O)
core   +1 more source

Determining the toxicological effects of indoor air pollution on both a healthy and an inflammatory-comprised model of the alveolar epithelial barrier in vitro

Particle and Fibre Toxicology
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation).
Kirsty Meldrum, Stephen J. Evans, Michael J. Burgum, Shareen H. Doak, Martin J. D. Clift   +4 more
doaj   +1 more source

Identification of two early blood biomarkers ACHE and CLEC12A for improved risk stratification of critically ill COVID-19 patients

Scientific Reports, 2023
In order to identify biomarkers for earlier prediction of COVID-19 outcome, we collected blood samples from patients with fatal outcomes (non-survivors) and with positive clinical outcomes (survivors) at ICU admission and after seven days.
Simone Kattner, Jan Müller, Karolina Glanz, Mehdi Manoochehri, Caroline Sylvester, Yevhen Vainshtein, Marc Moritz Berger, Thorsten Brenner, Kai Sohn   +8 more
doaj   +1 more source

From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights

Biomedicines, 2022
Although most same-stage non-alcoholic fatty liver disease (NAFLD) patients exhibit similar histologic sequelae, the underlying mechanisms appear to be highly heterogeneous.
Alexandra Gatzios, Matthias Rombaut, Karolien Buyl, Joery De Kock, Robim M. Rodrigues, Vera Rogiers, Tamara Vanhaecke, Joost Boeckmans   +7 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

In vitro regeneration and conservation of Indigo (Indigofera tinctoria L.) by slow growth induction [PDF]

, 2016
An efficient protocol for rapid in vitro clonal propagation has been established. Shoot proliferation was obtained from nodal explants in Murashige and Skoog medium supplemented with 1.0 mg L-1BA and 0.1 mg L-1 IAA.
B, S. K. (Soni), R, R. B. (Reghunath), S, A. (Alex), S, N. D. (Nair)   +3 more
core   +1 more source

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology

Diagnostic and Prognostic Research, 2022
Background Diagnosing ventilator-associated pneumonia (VAP) in an intensive care unit (ICU) is a complex process. Our aim was to collect, evaluate and represent the information relating to current clinical practice for the diagnosis of VAP in UK NHS ICUs,
W. S. Jones, J. Suklan, A. Winter, K. Green, T. Craven, A. Bruce, J. Mair, K. Dhaliwal, T. Walsh, A. J. Simpson, S. Graziadio, A. J. Allen   +11 more
doaj   +1 more source