Results 121 to 130 of about 23,163 (302)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

In Vivo and In Vitro Digestibility of a Complete Pelleted Feed in Horses

, 2012
COMPLETION OF AN IN VIVO DIGESTIBILITY TRIAL IN HORSES AND IN VITRO DIGESTIBILITY ASSAY DEVELOPMENT Cassandra Renee Sweeney In vivo analysis of equine feed digestibility has been the gold standard since the late 1800\u27s, although it can be time ...
Sweeney, Cassandra Renee
core   +2 more sources

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Effect of processing on nutritive value of corn cobs: Chemical composition and in vitro digestibility

, 2012
One of the causes of in low productivity of ruminants in Indonesia is the lack of continual availability of high quality feed. Agriculture by-product such as corn cob is potential to be used as roughage for ruminants. However its nutrient quality is low;
Yulistiani, Dwi, ., Supriati, Wina, E, Puastuti, W   +3 more
core   +2 more sources

In Vitro Digestibility Methodology Modification to Account for Horse Foregut Digestion Using Diets with Increased Soluble Carbohydrates and Protein

Fermentation
Ruminant in vitro methodologies use washing with neutral detergent solution (NDS) after incubation to mimic ruminant digestion, which is physiologically different compared to that of horses.
Ryon W. Springer, Trinette N. Jones, Michaela R. Plowman, Nichole M. Cherry, Walter F. Owsley, Tryon A. Wickersham, James P. Muir   +6 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Selection for increased in vitro digestibility improves feeding value of sorghum grain

, 1991
Six cannulated barrows and two hundred eighty-eight chicks were used in an experiment to determine the value of an in vitro protein digestibility assay (pepsin digest) for identification of sorghum parent Iines with improved nutritional value.
Richert, B T, B J Healy, Klopfenstein, C F, Joe D Hancock, Bramel-Cox, P.J., Hancock, Joe D, P J Bramel-Cox, Merle D Witt, B T Richert, Richert, B.T., Klopfenstein, C.F., C F Klopfenstein, Hancock, Joe D., Healy, B.J., Witt, Merle D, Healy, B J, Bramel-Cox, P J, Witt, Merle D.   +17 more
core   +2 more sources

Nutritional evaluation of partially defatted Hermetia illucens meal in rainbow trout (Oncorhynchus mykiss) diets under commercial-like conditions

Italian Journal of Animal Science
This study evaluated the potential of black soldier fly (BSF; Hermetia illucens) meal as a sustainable protein source in rainbow trout (Oncorhynchus mykiss; initial average weight of 117.1 g) diets under commercial-like conditions (water temperature of ...
Sara Bellezza Oddon, Ilaria Biasato, Francesco Gai, Manuela Renna, Carola Lussiana, Christian Caimi, Ikram Belghit, Gopika Radhakrishnan, Francisco Javier Moyano Lopez, María Jesús Aznar, Laura Gasco   +10 more
doaj   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source