Results 81 to 90 of about 117,867,101 (302)

In vitro prediction of whole ration digestibility

, 1979
In vitro digestibility measures allow to predict the in vivo digestibility of roughage organic matter with a better accuracy than the proximate chemical analysis.
Sylvie GIGER, Giger, Sylvie, Sauvant, Daniel, M. LILA, P. MORAND-FEHR, D. SAUVANT, Lila, Marc, Morand-Fehr, Pierre   +7 more
core   +1 more source

The proposed protein and carbohydrate ingredients and the acceptance of moist feed by newly hatched Bigfin reef squid (Sepioteuthis lessoniana)

Aquaculture Reports
Bigfin reef squid (Sepioteuthis lessoniana) begin to consume non-living food at least 20 days after hatching while they do not accept artificial diet during early phase of post-hatching.
Natthawut Chanlek, Jirapan Satjarak, Yuzuru Ikeda, Nutt Nuntapong, Karun Thongprajukaew   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Predicting methane production in dairy cows [PDF]

, 2013
Methane is a potent greenhouse gas, to which enteric fermentation from ruminants contributes significantly. Reliable and accurate predictions of methane (CH₄) production from dairy cows would be of interest to develop mitigation strategies and for ...
Ramin, Mohammad
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

In vitro efficacy of formulated protected fat from used cooking oil (UOC) on gas production, nutrient digestibility and rumen fermentation [PDF]

This study was designed to determine in vitro gas production, nutrients digestibility, and rumen fermentation products of supplementary formulated dietary protected fat (PF) from used cooking oil (UCO).
Budy, S. Iswan, Mohamad Asrol Kalam, Kalam, M. A., P.D. Muhd Sabri, Muhd Sabri, P. D., S. Iswan Budy   +5 more
core   +1 more source

FACTORS AFFECTING THE FIRST STAGE DIGESTION OF FORAGES USING FAECAL LIQUOR

Pakistan Veterinary Journal, 2003
An experiment was carried out to study the effect of duration of incubation on the digestibility with the aim to reduce the time of incubation of the first stage digestion.
A.A. Solangi
doaj