Results 71 to 80 of about 23,163 (302)

Preparation and In vitro Digestibility of Corn Starch Phosphodiester

, 2015
Purpose: To optimize the process conditions and analyze in vitro digestibility of corn starch phosphodiester prepared by sodium trimetaphosphate (STMP).Methods: By using response surface method, the effects of STMP concentration, pH, esterification ...
Zeng, J, Li, G, Li, F, Sun, J
core   +2 more sources

In-vitro screening of Kalahari browse species for rumen methane mitigation

Scientia Agricola, 2015
The nutritional value of browse foliage from the Thorny Kalahari Dune Bush veld of South Africa is not characterized. Most of this browse species is rich in tannin, but still palatable, and is consumed by ruminants during the dry season, as well as ...
Jacobus Johannes Francois Theart, Abubeker Hassen, Willem Adriaan van Niekerk, Belete Shenkute Gemeda   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Bromatological evaluation of eleven corn cultivars harvested at two cutting heights

Revista Brasileira de Zootecnia, 2012
The objective of this study was to evaluate the chemical composition and dry matter in vitro digestibility of stem, leaf, straw, cob and kernel fractions of eleven corn (Zea mays) cultivars, harvested at two cutting heights.
Hamilton Caetano, Mauro Dal Secco de Oliveira, José Esler de Freitas Júnior, Aníbal Coutinho do Rêgo, Marina Vieira de Carvalho, Francisco Palma Rennó   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

In Vitro Digestibility of Plastein Gel Prepared from Peptic Digest of Casein

, 1994
In vitro digestibility of plastein prepared from casein hydrolyzate was evaluated using proteolytic enzymes. Pancreatin was the most effective digestion enzyme, followed by trypsin, a-chymotrypsin, and pepsin was the least effective.
Perpustakaan UGM, i-lib
core   +1 more source

In vitro digestibility of Paspalum notatum in ruminal fluid of buffaloes and bovines

, 2020
The aim of this experiment was to evaluate the in vitro digestibility coefficients of dry matter (IVDMD) and in vitro organic matter digestibility (IVOMD) of mature Paspalum notatum grass in buffaloes (Bubalus bubalis) and cattle (Bosindicus).
Criscioni, P., Zaracho, E., Torres, M., Aquino, D., Valiente, O. L.   +4 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source