Results 71 to 80 of about 74,947 (311)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The proposed protein and carbohydrate ingredients and the acceptance of moist feed by newly hatched Bigfin reef squid (Sepioteuthis lessoniana)

Aquaculture Reports
Bigfin reef squid (Sepioteuthis lessoniana) begin to consume non-living food at least 20 days after hatching while they do not accept artificial diet during early phase of post-hatching.
Natthawut Chanlek, Jirapan Satjarak, Yuzuru Ikeda, Nutt Nuntapong, Karun Thongprajukaew   +4 more
doaj   +1 more source

The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs [PDF]

, 2009
Depending on type and inclusion level, dietary fibre may increase and maintain satiety and postpone the onset of hunger. This 7-week study evaluated the effect of fibre fermentability on physiological satiety-related metabolites and voluntary food intake
Bosch, G., Hendriks, W.H., Hesta, M., Holst, J.J., Janssens, G.P.J., Poel, A.F.B., van der, Verbrugghe, A.   +6 more
core   +2 more sources

In vitro digestibility of Bacillus fermented soya bean

International Journal of Food Microbiology, 2000
Bacillus fermented legume products include among others dawadawa and soumbala made from African locust bean, and natto and kinema made from soya bean. Bacillus subtilis is the dominant species involved in the fermentation. During Bacillus fermentation for 48 h of autoclaved soya bean the quantity of soluble and dialyzable matter increased from 22% and ...
Kiers, J.L., Laeken, A.E.A., Rombouts, F.M., Nout, M.J.R.   +3 more
openaire   +4 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Quantification of nutrient supply in forage-based diets for beef cattle [PDF]

, 2009
End of Project ReportIntroduction Cattle rearing systems in Ireland are predominantly grass-based as 80% of agricultural land is dedicated to grassland (silage, hay and pasture) (CSO, 2007).
McGee, Mark, O'Kiely, Padraig, Owens, David   +2 more
core  

A microfluidic model for infantile in vitro digestions: Characterization of lactoferrin digestion

SLAS Technology
We present a miniaturized, flow-through model for infantile in vitro digestions, following up on our previously published in vitro digestive system for adults. Microfluidic 'chaotic' mixers were employed as microreactors to help emulate the biochemical processing going on in the infantile stomach and intestine.
Pim de Haan, Daigo Natsuhara, Vassilis Triantis, Takayuki Shibata, Elisabeth Verpoorte   +4 more
openaire   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Impact of bacteria and yeast with probiotic properties on performance, digestibility, health status and gut environment of growing pigs in Vietnam [PDF]

, 2010
This thesis aimed to evaluate the effects of six lactic acid bacteria (LAB) strains and Bacillus subtilis H4, Saccharomyces boulardii Sb, and a microbial enzyme mixture, supplemented to basal diets on the performance, diet digestibility, health status ...
Giang, Hoang Huong
core