Results 131 to 140 of about 114,834,543 (300)

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Investigation of lipid digestion by fungal and porcine lipase supplementation for severe pancreatic insufficiency using the in vitro dynamic TIM model

Heliyon
Background: Exocrine pancreatic insufficiency is caused by insufficient secretion or limited activity of pancreatic enzymes leading to inadequate food digestion.
Tânia Martins Garcia, Annet Maathuis, Ronald Schilderink, Ioannis Vrasidas, Alexander Iphöfer, Meinolf Wonnemann, Bartosz Lipowicz   +6 more
doaj   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

In Vitro Gastrointestinal Digestion Model To Monitor The Antioxidant Properties And Bioaccessbility Of Phenolic Extracts From Elderberry (sambucus Nigra L.) [PDF]

, 2016
This study performed an in vitro gastrointestinal digestion model to monitor the antioxidant properties of phenolic extracts derived from the elderberry (Sambucus nigra L.).
Zhou, Ninghui
core   +1 more source

Current advances for in vitro protein digestibility

Frontiers in Nutrition
Protein is an essential macronutrient in our diet, source of nitrogen and essential amino acids, but the biological utilization of dietary protein depends on its digestibility and the absorption of amino acids and peptides in the gastrointestinal tract ...
Guillermo Santos-Sánchez, Beatriz Miralles, André Brodkorb, Didier Dupont, Lotti Egger, Isidra Recio   +5 more
doaj   +1 more source

Milk digestion peptidomics: Tracking caseinophosphopeptides in simulated gastrointestinal digestion

, 2019
The dynamics of caseinophosphopeptides (CPP) in simulated gastrointestinal digestion was studied. CPP in the undigested milk and in vitro simulated gastrointestinal hydrolysates were enriched using immobilized titanium (IV) ion affinity chromatography ...
Yu, Yang, Qi, Yanxia, Jin, Yan
core   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

A novel biorelevant in vitro dynamic digestion simulator reproducing the biomechanics of the gastrointestinal tract

, 2022
This conference is a major event in the field of Food, Nutrition and Health. It is organized in the frame of the INFOGEST research network(www.cost-infogest.eu) whose objective is to “improve the health properties of food by sharing our knowledge on the ...
Feng, Jiajun, Le Feunteun, Steven, Ménard, Olivia, Dupont, Didier, Greco, Ines, Jeantet, Romain   +5 more
core   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Digestion characteristics of sweet potato (Ipomoea batatas) polysaccharide in vitro and its relieving effect on ability to relieve exercise fatigue in mice

Food Production, Processing and Nutrition
The characteristics of Ipomoea batatas polysaccharide (IBP) in vitro and its anti-fatigue effects on exercise fatigue in mice were investigated. The dynamic division of IBP was simulated in vitro, and the structural changes in IBP were analyzed by ...
Xiao Gong, Wei-ze Mao, Tian Xu, Le Luo, Xiao-jing Chen   +4 more
doaj   +1 more source