Results 151 to 160 of about 114,819,952 (302)

Effects of Micronization on Morphology and Functional Attributes of Radio Frequency Stabilized Brown Millet and Millet Bran

open access: yesShipin gongye ke-ji
Brown millet and millet bran are rich in nutrients. After stabilization treatment, they are easy to store and transport. However, it is difficult for them to be accepted as food ingredients by consumers due to their poor texture and taste.
Chen CHEN   +4 more
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

open access: yesAdvanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang   +9 more
wiley   +1 more source

Comparative assessment of Dendrobium officinale polysaccharides and enzymatically derived oligosaccharides: Structural characterization and in vitro metabolic function modulation and gut microbiota regulation

open access: yesIndustrial Crops and Products
Metabolic dysregulation is closely linked to impaired glucose metabolism and gut microbiota imbalance, and dietary carbohydrates have emerged as important modulators of these processes.
Yuan Li   +8 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Heat-time-controlled chickpea protein aggregates: structure–function–digestibility interplay and Pickering emulsion performance

open access: yesFood Chemistry: X
This study systematically investigated the modulation effects of heating duration (0–60 min) on the structure, functional properties, and Pickering emulsion performance of chickpea protein aggregates (CPAs).
Yunxia Tan   +11 more
doaj   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu   +10 more
wiley   +1 more source

Phytochemical compounds, antioxidant activity, and antiproliferative activity of sesame seeds as affected by simulated digestion

open access: yesFood Chemistry: X
Antioxidant and antiproliferative activities in white and black sesame seeds were investigated during a simulated in vitro digestion. The levels of phenolic compounds, flavonoids and oxygen radical absorbance capacity (ORAC) values of sesame seeds ...
Lin Zhou   +6 more
doaj   +1 more source

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