Results 201 to 210 of about 51,909 (235)
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Prospects for spermatogenesis in vitro
Theriogenology, 2003In recent years, extraordinary progress has been made in a broad range of reproductive technologies, including spermatogonial transplantation in the male. However, effective procedures for the complete recapitulation of spermatogenesis in vitro, including meiosis, have remained elusive.
J E, Parks +3 more
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In vitro spermatogenesis: Why meiotic checkpoints matter
2023Successful in vitro spermatogenesis would generate functional haploid spermatids, and thus, form the basis for novel approaches to treat patients with impaired spermatogenesis or develop alternative strategies for male fertility preservation. Several culture strategies, including cell cultures using various stem cells and ex vivo cultures of testicular
Lei, Qijing +2 more
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Spermatogenesis In Vitro: Searching for In Vivo Correlates
1987The development of methodology for the study of spermatogenesis in vitro has been a major task that remained elusive (Wolff and Haffen, 1965; Steinberger, 1975). Significant advances have been reported in the culture of meiotic cells of lilaceous plants (Hotta et al., 1966), and spermatogenic cells of Xenopus (Risley, 1983) and Drosophila (Liebrich ...
A L, Kierszenbaum +3 more
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SPERMATOGENESIS IN VITRO: COMPLETION OF MEIOSIS AND EARLY SPERMIOGENESIS
Endocrinology, 1983In vitro formation of haploid spermatids has not been convincingly demonstrated in mammals. To investigate this problem we selected defined segments of rat seminiferous tubules containing late pachytene and diakinetic primary spermatocytes (Stages XII and XIII of the cycle) for culture in a chemically defined medium.
M, Parvinen +5 more
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In Vitro Spermatogenesis Using an Organ Culture Technique
2012Research on in vitro spermatogenesis has a long history and remained to be an unaccomplished task until very recently. In 2010, we succeeded in producing murine sperm from primitive spermatogonia using an organ culture method. The fertility of the sperm or haploid spermatids was demonstrated by microinsemination.
Tetsuhiro, Yokonishi +3 more
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High glucose levels affect spermatogenesis: an in vitro approach
Reproduction, Fertility and Development, 2016Besides known factors that may cause male infertility, systemic diseases such as diabetes mellitus may further exacerbate a decline in male fertility. This metabolic disease, clinically characterised by a hyperglycaemic phenotype, has devastating consequences in terms of human health, with reproductive dysfunction being one of the associated clinical ...
Renata S, Tavares +5 more
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Mouse In Vitro Spermatogenesis on 3D Bioprinted Scaffolds
Testes have a complex architecture that is compartmentalized into seminiferous tubules with a diameter of approximatively 200 μm in which the germ cells differentiate, surrounded by a basement membrane and interstitium. 3D bioprinting might be used to recreate the compartmentalized testicular architecture in vitro.Guillaume, Richer +4 more
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