Results 251 to 260 of about 117,900,808 (282)
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Cyclohexylamine mutagenicity: An in vivo evaluation utilizing fetal lambs
Mutation Research, 1974Summary The in vivo effects of cyclohexylamine (CHA) upon the segregation apparatus and chromosome morphology of mitogenically capable lymphocytes obtained from the peripheral circulating blood tissue of living fetal lambs in utero were evaluated. CHA proved to be a clastogen in vivo .
J H, Turner, D L, Hutchinson
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Mutagenic potential of temozolomide in bone marrow cells in vivo
Blood, 2006Therapy-related myeloid leukemias (t-MLs) occur in as many as 5% to 10% of patients who are otherwise cured of a primary neoplasm with aggressive multimodal regimens. Many patients with t-MLs or therapy-related myelodysplastic syndrome (t-MDS) have previously received chemotherapeutic agents ...
Hartmut, Geiger +5 more
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EPA use of in vivo germ cell mutagenicity data
Environmental and Molecular Mutagenesis, 1991AbstractThe Toxic Substances Control Act (TSCA) provides the U.S. Environmental Protection Agency, Office of Toxic Substances (EPA, OTS) with the authority to regulate chemical use by requiring testing and use restrictions as appropriate to protect human health.
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Evaluation of the mutagenicity of a-dihydroergocryptine in vitro and in vivo.
Arzneimittel-Forschung, 1994The mutagenic potential of the ergot alkaloid a-dihydroergocryptine (a-DEC, CAS 14271-05-7) was assessed in a series of 5 assays designed to measure gene mutation, chromosomal damage and primary DNA damage. All tests were carried out in accordance with appropriate EEC and OECD Guidelines.
K, Adams +6 more
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Mutagenicity tests on epristeride in vitro and in vivo.
Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999To evaluate the genetic effects of epristeride (Epr), a new prospective drug for treating benign prostatic hyperplasia.1) Assaying reverse mutation in histidine nutritional deficiency strain of Salmonella typhimurium 2) detecting chromosome aberrations in Chinese hamster lung cells (CHL); 3) micronucleus assays of mouse bone marrow; 4) counting sperm ...
X L, Wang +4 more
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In vivo studies on the mutagenicity of arsenic
Mutation Research/Environmental Mutagenesis and Related Subjects, 1985Gh. Deknudt +4 more
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In vivo mutagenicity of hexavalent chromium
Mutation Research/Environmental Mutagenesis and Related Subjects, 1995S. Itoh, H. Shimada
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Mutagenicity of methylglyoxal in vitro and in vivo
Mutation Research/Environmental Mutagenesis and Related Subjects, 1990L. Migliore +4 more
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