Results 31 to 40 of about 460,985 (293)

Praziquantel/Cyclodextrin Inclusion Complexes [PDF]

open access: yes, 2022
Praziquantel (PZQ) is an anthelmintic drug used for therapy and prevention of schistosomiasis.1 The drug is administrated as a racemate, where R- enantiomer is eutomer, while S-enantiomer is responsible for extremely bitter taste of the drug. PZQ has aqueous solubility of 0.04 mg/mL, and is classified as type II drug according to the Biopharmaceutical ...
openaire   +2 more sources

Cyclodextrin stabilised emulsions and cyclodextrinosomes [PDF]

open access: yes, 2013
We report the preparation of o/w emulsions stabilised by microcrystals of cyclodextrin-oil inclusion complexes. The inclusion complexes are formed by threading cyclodextrins from the aqueous phase on n-tetradecane or silicone oil molecules from the ...
Mathapa, Baghali G., Paunov, Vesselin N.
core   +1 more source

A superior preparation method for daidzein-hydroxypropyl-β-cyclodextrin complexes with improved solubility and dissolution: Supercritical fluid process

open access: yesActa Pharmaceutica, 2017
Advantages of the supercritical fluid (SCF) process compared to the conventional solution stirring method (CSSM) in the preparation of daidzein-hydroxypropyl-β-cyclodextrin (HPβCD) complexes were investigated.
Pan Hao   +5 more
doaj   +1 more source

Preparation and Characterization of Inclusion Complexes of β-Cyclodextrin and Phenolics from Wheat Bran by Combination of Experimental and Computational Techniques

open access: yesMolecules, 2020
Bitterness often associated with whole wheat products may be related to phenolics in the bran. Cyclodextrins (CDs) are known to form inclusion complexes. The objective was to form inclusion complexes between β-CD and wheat phenolics. Pure phenolic acids (
Tuba Simsek   +3 more
doaj   +1 more source

Fluorescence study of tetracaine–cyclodextrin inclusion complexes [PDF]

open access: yes, 2010
The steady-state fluorescence emission from the local anaesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β- and γ-cyclodextrin (CD) was investigated at various pH values.
Brandariz, Isabel   +2 more
core   +2 more sources

Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac

open access: yesJournal of Pharmacy and Bioallied Sciences, 2011
The objective of the present investigation was to study the effect of β-cyclodextrin (β-CD) on the in vitro dissolution of aceclofenac (AF) from molecular inclusion complexes. Aceclofenac molecular inclusion complexes in 1:1 and 1:2 M ratio were prepared
Kamal Dua   +3 more
doaj   +1 more source

Vibrational properties of inclusion complexes: the case of indomethacin-cyclodextrin

open access: yes, 2006
Vibrational properties of inclusion complexes with cyclodextrins are studied by means of Raman spectroscopy and numerical simulation. In particular, Raman spectra of the non-steroidal, anti-inflammatory drug indomethacin undergo notable changes in the ...
Anderson A.   +8 more
core   +1 more source

The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes. [PDF]

open access: yes, 2015
A novel biocompatible and biodegradable drug-delivery nanoparticle (NP) has been developed to minimize the severe side effects of the poorly water-soluble anticancer drug paclitaxel (PTX) for clinical use.
Chen, R   +5 more
core   +2 more sources

Supramolecular Gelatin Networks Based on Inclusion Complexes [PDF]

open access: yesMacromolecular Bioscience, 2020
AbstractHydrogel forming physical networks based on gelatin are an attractive approach toward multifunctional biomaterials with the option of reshaping, self‐healing, and stimuli‐sensitivity. However, it is challenging to design such gelatin‐based hydrogels to be stable at body temperature.
Candy Löwenberg   +4 more
openaire   +4 more sources

Anti-atherosclerotic effect of lipid/cholesterol-cyclodextrin inclusion complexes similar to free cyclodextrins in ApoE-/- mice fed a high-fat diet

open access: yesCarbohydrate Polymer Technologies and Applications
Cyclodextrins have long been used as a drug excipient (e.g., drug-cyclodextrin inclusion complex) to ameliorate the water solubility and taste of drugs.
Yuanfang Li   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy