Results 11 to 20 of about 143,348 (263)
Cyclodextrin Inclusion Complexes with Hydrocortisone-Type Corticosteroids [PDF]
The hydrocortisone-type corticosteroid (HTC) group includes valuable active pharmaceutical ingredients (APIs) such as hydrocortisone, hydrocortisone acetate, cortisone acetate, tixocortol pivalate, prednisolone, methylprednisolone, and prednisone ...
Aleksandra Kowalska, Łukasz Szeleszczuk
doaj +2 more sources
Simazine inclusion complexes with cucurbiturils (n = 6–8): experimental and molecular dynamics studies [PDF]
Simazine (SIM) inclusion complexes with cucurbit[n]uril, CBn, (n = 6–8), have been studied in both aqueous solutions and solid states. NMR measurements were taken in DMSO.
Abdalla A. Elbashir +3 more
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Development of essential oils inclusion complexes: a nanotechnology approach with enhanced thermal and light stability [PDF]
Essential oils (EOs) are volatile compounds that may have antimicrobial and antioxidant properties. Despite their potential application, low water solubility and chemical instability are limiting factors.
Fernanda Ramalho Procopio +6 more
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Defeasible Inclusions in Low-Complexity DLs [PDF]
Some of the applications of OWL and RDF (e.g. biomedical knowledge representation and semantic policy formulation) call for extensions of these languages with nonmonotonic constructs such as inheritance with overriding. Nonmonotonic description logics have been studied for many years, however no practical such knowledge representation languages exist ...
BONATTI, PIERO ANDREA +2 more
openaire +4 more sources
Zinc diethyldithiocarbamate (Zn (DDC)2), a disulfiram metabolite (anti-alcoholism drug), has shown a strong anti-cancer activity in vitro. However, its application was limited by its low aqueous solubility and rapid metabolism.
Ayşe Kaya +6 more
doaj +1 more source
Investigation and Physicochemical Characterization of Binary Febuxostat- Sulfobutyl Ether β -Cyclodextrin Inclusion Complexes [PDF]
Background: Febuxostat (FBX) a non-purine, xanthine oxidase inhibitor that is commonly indicated for the treatment of chronic gout. Yet, it is suffering from limited application as it belongs to The BCS II class that exhibit poor solubility.
Wedad Sakran +3 more
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The aim of the present study was to manufacture new orally disintegrating tablets containing nimodipine–hydroxypropyl-β-cyclodextrin and nimodipine–methyl-β-cyclodextrin inclusion complexes.
Marian Novac +9 more
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The aim of this study was to improve the solubility of amiodarone hydrochloride (AMD) and the drug release using its inclusion complexes with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD).
Andreea Creteanu +7 more
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Antimicrobial activity of fusidic acid inclusion complexes
Objectives: To synthesize and characterize the inclusion complexes of fusidic acid with β – cyclodextrin, followed by the evaluation of their antimicrobial activity against pure strain (Staphylococcus aureus ATCC 25,923) and isolated Staphylococcus from ...
Eleonora Marian +10 more
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Cyclodextrins and Their Derivatives as Drug Stability Modifiers
Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion complexes with many substances.
Virginia Aiassa +3 more
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