Results 21 to 30 of about 135,044 (257)

Study on the Role of the Inclusion Complexes with 2-Hydroxypropyl-β-cyclodextrin for Oral Administration of Amiodarone

International Journal of Polymer Science, 2019
The aim of this study was to improve the solubility of amiodarone hydrochloride (AMD) and the drug release using its inclusion complexes with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD).
Andreea Creteanu, Daniela Pamfil, Cornelia Vasile, Gladiola Tantaru, Cristina Mihaela Ghiciuc, Lacramioara Ochiuz, Alina Ghilan, Ana Maria Macsim   +7 more
doaj   +1 more source

Cyclodextrins and Their Derivatives as Drug Stability Modifiers

Pharmaceuticals, 2023
Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion complexes with many substances.
Virginia Aiassa, Claudia Garnero, Ariana Zoppi, Marcela R. Longhi   +3 more
doaj   +1 more source

Antimicrobial activity of fusidic acid inclusion complexes

International Journal of Infectious Diseases, 2020
Objectives: To synthesize and characterize the inclusion complexes of fusidic acid with β – cyclodextrin, followed by the evaluation of their antimicrobial activity against pure strain (Staphylococcus aureus ATCC 25,923) and isolated Staphylococcus from ...
Eleonora Marian, Bogdan Tita, Narcis Duteanu, Laura Vicas, Stefania Ciocan, Tunde Jurca, Liana Antal, Otilia Tica, Mariana Mureşan, Annamaria Pallag, Otilia Micle   +10 more
doaj   +1 more source

Preparation, characterization, and antibacterial activity of plaunotol and plaunoi extracts complexed with hydroxypropyl-β-cyclodextrin

Saudi Pharmaceutical Journal, 2022
Croton stellatopilosus (Plaunoi) leaves accumulate several diterpenes and possess various pharmacological activities. The present study aimed to prepare, characterize and assess the antibacterial activity of inclusion complexes prepared by mixing ...
Wai Mi Aung, Sarunyoo Songkro, Supreedee Songkharak, Nattha Kaewnopparat, Juraithip Wungsintaweekul   +4 more
doaj   +1 more source

Cyclodextrin Encapsulated pH Sensitive Dyes as Fluorescent Cellular Probes: Self-Aggregation and In Vitro Assessments

Molecules, 2020
We have designed and synthesized a series of novel, supramolecular, long-lived fluorescent probes based on the host-guest inclusion complexes formation between fluorescent indolizinyl-pyridinium salts and β-cyclodextrin.
Monica-Cornelia Sardaru, Oana Carp, Elena-Laura Ursu, Anda-Mihaela Craciun, Corneliu Cojocaru, Mihaela Silion, Vladyslava Kovalska, Ionel Mangalagiu, Ramona Danac, Alexandru Rotaru   +9 more
doaj   +1 more source

Short Review on the Biological Activity of Cyclodextrin-Drug Inclusion Complexes Applicable in Veterinary Therapy

Molecules, 2023
Cyclodextrins (CDs) are a family of carrier molecules used to improve the pharmacokinetic parameters of therapeutic molecules. These cyclic oligosaccharides have medical and pharmaceutical applications by being able to form inclusion complexes with ...
Mariana Grecu, Bogdan Minea, Liliana-Georgeta Foia, Andra-Cristina Bostanaru-Iliescu, Liviu Miron, Valentin Nastasa, Mihai Mares   +6 more
doaj   +1 more source

A superior preparation method for daidzein-hydroxypropyl-β-cyclodextrin complexes with improved solubility and dissolution: Supercritical fluid process

Acta Pharmaceutica, 2017
Advantages of the supercritical fluid (SCF) process compared to the conventional solution stirring method (CSSM) in the preparation of daidzein-hydroxypropyl-β-cyclodextrin (HPβCD) complexes were investigated.
Pan Hao, Wang Han-Bing, Yu Yi-Bin, Cheng Bing-Chao, Wang Xiao-Yu, Li Ying   +5 more
doaj   +1 more source

Propriedades e aplicações recentes das ciclodextrinas Properties and recent applications of cyclodextrins

Química Nova, 2008
Cyclodextrins (CDs) are cyclic oligosaccharides comprised of six or more glucose units connected by alpha-1,4 bonds. They have hydrophobic cavities with a hydrophilic exterior, and are versatile receptors for a variety of substrates.
Cristina de Garcia Venturini, Jaqueline Nicolini, Clodoaldo Machado, Vanderlei Gageiro Machado   +3 more
doaj   +1 more source

Preparation and Characterization of Inclusion Complexes of β-Cyclodextrin and Phenolics from Wheat Bran by Combination of Experimental and Computational Techniques

Molecules, 2020
Bitterness often associated with whole wheat products may be related to phenolics in the bran. Cyclodextrins (CDs) are known to form inclusion complexes. The objective was to form inclusion complexes between β-CD and wheat phenolics. Pure phenolic acids (
Tuba Simsek, Bakhtiyor Rasulev, Christian Mayer, Senay Simsek   +3 more
doaj   +1 more source

Anti-atherosclerotic effect of lipid/cholesterol-cyclodextrin inclusion complexes similar to free cyclodextrins in ApoE-/- mice fed a high-fat diet

Carbohydrate Polymer Technologies and Applications
Cyclodextrins have long been used as a drug excipient (e.g., drug-cyclodextrin inclusion complex) to ameliorate the water solubility and taste of drugs.
Yuanfang Li, Yuan Zhang, Mengyi Lan, Zhilu Fan, Tingting Gong, Langtao Xu, Tong Rong, Kun Wang, Huaying Wang, Meiying Ao, Yong Chen   +10 more
doaj   +1 more source