Results 31 to 40 of about 466,743 (288)

Cyclodextrins: Concept to applications, regulatory issues and challenges [PDF]

Nanomedicine Research Journal, 2020
Background: Solubility properties of drugs intensify a crucial role during the formulation development process. Aqueous solubility is one of the most significant factors concerning drug bioavailability analysis.
Azeez Mohammad, Sumer Singh, Suryakanta Swain   +2 more
doaj   +1 more source

Antimicrobial activity of fusidic acid inclusion complexes

International Journal of Infectious Diseases, 2020
Objectives: To synthesize and characterize the inclusion complexes of fusidic acid with β – cyclodextrin, followed by the evaluation of their antimicrobial activity against pure strain (Staphylococcus aureus ATCC 25,923) and isolated Staphylococcus from ...
Eleonora Marian, Bogdan Tita, Narcis Duteanu, Laura Vicas, Stefania Ciocan, Tunde Jurca, Liana Antal, Otilia Tica, Mariana Mureşan, Annamaria Pallag, Otilia Micle   +10 more
doaj   +1 more source

Short Review on the Biological Activity of Cyclodextrin-Drug Inclusion Complexes Applicable in Veterinary Therapy

Molecules, 2023
Cyclodextrins (CDs) are a family of carrier molecules used to improve the pharmacokinetic parameters of therapeutic molecules. These cyclic oligosaccharides have medical and pharmaceutical applications by being able to form inclusion complexes with ...
Mariana Grecu, Bogdan Minea, Liliana-Georgeta Foia, Andra-Cristina Bostanaru-Iliescu, Liviu Miron, Valentin Nastasa, Mihai Mares   +6 more
doaj   +1 more source

Solid-state flurbiprofen and methyl-β-cyclodextrin inclusion complexes prepared using a single-step, organic solvent-free supercritical fluid process [PDF]

, 2016
The aim of this study was to enhance the apparent solubility and dissolution properties of flurbiprofen through inclusion complexation with cyclodextrins.
Al-Marzouqi, Al-Marzouqi, Ambade, Anderson, Aroso, Baek, Banchero, Bandi, Bontha, Bruce David Alexander, Charman, Charoenchaitrakool, Cirri, Davies, Govindarajan, Gupta, Guyot, Habib, He, Heasman, Herzfeldt, Higuchi, Jiang, Kaialy, Khan, Kim, Kompella, Lee, Li, Lin, Marques, Martin J. Snowden, Muhammad U. Ghori, Muraoka, Oh, Park, Rudrangi, Rudrangi, Rudrangi, Shashi Ravi Suman Rudrangi, Sunkara, Takagi, Tokumura, Türk, Varma, Vega, Vivek Trivedi, Waseem Kaialy, Weerapol, York   +49 more
core   +2 more sources

Vibrational properties of inclusion complexes: the case of indomethacin-cyclodextrin

, 2006
Vibrational properties of inclusion complexes with cyclodextrins are studied by means of Raman spectroscopy and numerical simulation. In particular, Raman spectra of the non-steroidal, anti-inflammatory drug indomethacin undergo notable changes in the ...
Anderson A., Barbara Rossi, Choi S. H., Gabriele Viliani, Giorgina Scarduelli, Graziano Guella, Ines Mancini, Lee A. S., Paolo Verrocchio   +8 more
core   +1 more source

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release [PDF]

, 2011
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug ...
A Al-Omar, A Latrofa, A Miro, A Trapani, A Vyas, AC Jain, AK Upadhyay, AL Nielsen, AS Hoffman, B Haeberlin, B Pose-Vilarnovo, BN Naidu, C Cannavà, C Rodriguez-Tenreiro, C Rupp, C-Y Chen, Catarina Carvalho, Claúdia Conduto, CM Buchanan, CM Fernandes, D Duchêne, D Duchêne, EA Zannou, EY Kim, F Frézard, F Hirayama, G Corti, G Gladys, G Pescitelli, G Trapani, G Wenz, G Zingone, GL Amidon, H Blode, H Hamada, H Matsuda, H Namazi, H Taira, H Yano, HA Archontaki, Helena M. Cabral Marques, HH Sigurdsson, HS Ganapathy, HS Woldum, Inês Sanches, IV Terekhova, J Cheng, J Králová, J Savolainen, J Szejtli, J Szejtli, J Xiong, JJ García-Rodriguez, João Arrais, JP Venter, JR Moyano, JS Smith, JW Wong, K Dua, K Minami, K Motoyama, K Nakanishi, K Okimoto, K Okimoto, K Okimoto, K Terao, K Udo, K Uekama, K Uekama, K Uekama, K-H Frӧmming, KP Chowdary, L Ribeiro, L Szente, L Trichard, M Agüeros, M Agüeros, M Charoenchaitrakool, M Cirri, M Echezarreta-López, M Fukuda, M Jug, M Jug, M Kamada, M Prabaharan, M Roux, M Sauceau, M Temtem, M Türk, M Usuda, M Yoshinari, M-J Zou, ME Zugasti, MT Esclusa-Díaz, MZI Khan, N Mourtzis, N Patel, N Zerrouk, N Zhang, N Özdemir, P Jansook, P Mura, P Mura, P Mura, P Mura, P Mura, Patrícia Pontes, Paulo José Salústio, PJ Salústio, R Cavalli, R Cavalli, R Challa, R Ficarra, R Garg, R Stancanelli, RL Carrier, S Petralito, S Péroche, S Sajeesh, S Sotthivirat, S Sotthivirat, S Szejtli, S Tommasini, S-Y Lee, Shishu, SM Badr-Eldin, T Endo, T Higashi, T Higashi, T Irie, T Loftsson, T Loftsson, T Loftsson, T Vasconcelos, T Yamanoi, V Burckbuchler, V Lemesle-Lamache, VM Rao, W Ling, W Sajomsang, X Lu, X Wen, X-M Liu, Y He, Y Ikeda, Y Ikeda, Y Liu, Y Liu, Y Lu, Y Tozuka, Y Zhou, Y-Z Du, Z Lu, Z Wang   +153 more
core   +1 more source

A superior preparation method for daidzein-hydroxypropyl-β-cyclodextrin complexes with improved solubility and dissolution: Supercritical fluid process

Acta Pharmaceutica, 2017
Advantages of the supercritical fluid (SCF) process compared to the conventional solution stirring method (CSSM) in the preparation of daidzein-hydroxypropyl-β-cyclodextrin (HPβCD) complexes were investigated.
Pan Hao, Wang Han-Bing, Yu Yi-Bin, Cheng Bing-Chao, Wang Xiao-Yu, Li Ying   +5 more
doaj   +1 more source

Preparation and Characterization of Inclusion Complexes of β-Cyclodextrin and Phenolics from Wheat Bran by Combination of Experimental and Computational Techniques

Molecules, 2020
Bitterness often associated with whole wheat products may be related to phenolics in the bran. Cyclodextrins (CDs) are known to form inclusion complexes. The objective was to form inclusion complexes between β-CD and wheat phenolics. Pure phenolic acids (
Tuba Simsek, Bakhtiyor Rasulev, Christian Mayer, Senay Simsek   +3 more
doaj   +1 more source

Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac

Journal of Pharmacy and Bioallied Sciences, 2011
The objective of the present investigation was to study the effect of β-cyclodextrin (β-CD) on the in vitro dissolution of aceclofenac (AF) from molecular inclusion complexes. Aceclofenac molecular inclusion complexes in 1:1 and 1:2 M ratio were prepared
Kamal Dua, Kavita Pabreja, M V Ramana, Vinny Lather   +3 more
doaj   +1 more source

The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes. [PDF]

, 2015
A novel biocompatible and biodegradable drug-delivery nanoparticle (NP) has been developed to minimize the severe side effects of the poorly water-soluble anticancer drug paclitaxel (PTX) for clinical use.
Chen, R, Chen, YZ, Gao, F, Lou, KY, Wang, Y, Ye, YJ   +5 more
core   +2 more sources