Results 11 to 20 of about 21,748 (299)
Indian Journal of Endocrinology and Metabolism, 2012 Nutrient excess results in systemic inflammation in diabetes contributing to insulin resistance, dyslipidaemia and increased cardiovascular risk. GLP-1 agonists and DPP-4 inhibitors, which are now well accepted therapies for diabetes may play a unique ...
Amitabh Hatwal
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Pleiotropic effects of incretins
Indian Journal of Endocrinology and Metabolism, 2012 Drugs that augment the incretin system [glucagon like peptide (GLP) agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors] represent a novel class of anti-hyperglycemic agents that have shown to improve the health and survival of beta-cells (improvement
Vishal Gupta
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Clinical Pharmacology: Advances and Applications, 2018 Simone Perna,1 Manuela Mainardi,2 Paolo Astrone,2 Carlotta Gozzer,3 Anna Biava,1 Ruben Bacchio,3 Daniele Spadaccini,3 Sebastiano Bruno Solerte,2 Mariangela Rondanelli4 1Department of Biology, College of Science, University of Bahrain, Sakhir Campus ...
Perna S +8 more
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Do incretins improve endothelial function? [PDF]
Cardiovascular Diabetology, 2014 An impaired endothelial function has been recognized in the early stage of atherosclerosis, and is a major factor affecting the future development of cardiovascular events.
Jun-ichi Oyama +2 more
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Diabetologia, 2023 Glucagon-like peptide-1 receptor agonists (GLP-1RAs, incretin mimetics) and dipeptidyl peptidase-4 inhibitors (DPP-4is, incretin enhancers) are glucose-lowering therapies with proven cardiovascular safety, but their effect on microvascular disease is not
Jonathan Goldney, J. Sargeant, M. Davies
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The Role of Incretins on Insulin Function and Glucose Homeostasis
Endocrinology, 2021 The incretin effect—the amplification of insulin secretion after oral vs intravenous administration of glucose as a mean to improve glucose tolerance—was suspected even before insulin was discovered, and today we know that the effect is due to the ...
J. Holst, L. Gasbjerg, M. Rosenkilde
semanticscholar +1 more source
Incretin‐based therapies [PDF]
Journal of Diabetes, 2012 AbstractIncretin‐based therapies have established a foothold in the diabetes armamentarium through the introduction of oral dipeptidyl peptidase‐4 inhibitors and the injectable class, the glucagon‐like peptide‐1 receptor agonists. In 2009, the American Diabetes Association and European Association for the Study of Diabetes authored a revised consensus ...
Stonehouse, Anthony H +2 more
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Journal of Physiology, 2022 Insulin infusion increases skeletal muscle microvascular blood flow (MBF) in healthy people but is impaired during insulin resistance. However, we have shown that eliciting insulin secretion via oral glucose loading in healthy people impairs muscle MBF ...
K. Roberts-Thomson +6 more
semanticscholar +1 more source
The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery
Frontiers in Genetics, 2021 Type 2 diabetes mellitus (T2DM) is one of the most prominent and socially significant problems. The present study aimed to identify the mechanisms of interaction of critical regulators of carbohydrate metabolism using bioinformatics and experimental ...
D. Skuratovskaia +7 more
semanticscholar +1 more source
Scientific Reports, 2022 It has not been elucidated whether incretins affect insulin clearance in type 2 diabetes (T2D). We aimed exploring possible associations between insulin clearance and endogenously secreted or exogenously administered incretins in T2D patients. Twenty T2D
Andrea Tura +4 more
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