Results 71 to 80 of about 8,133 (247)

Transglycosylated Starch Modulates the Gut Microbiome and Expression of Genes Related to Lipid Synthesis in Liver and Adipose Tissue of Pigs

Frontiers in Microbiology, 2018
Dietary inclusion of resistant starches can promote host health through modulation of the gastrointestinal microbiota, short-chain fatty acid (SCFA) profiles, and lipid metabolism. This study investigated the impact of a transglycosylated cornstarch (TGS)
Monica A. Newman, Renée M. Petri, Dietmar Grüll, Qendrim Zebeli, Barbara U. Metzler-Zebeli   +4 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Impact of Dapagliflozin on MRI‐Derived Epicardial Adipose Tissue: Secondary Imaging Analysis of a Randomized Trial

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium–glucose cotransporter‐2 (SGLT2) inhibitors reduce EAT thickness in patients with type 2 diabetes mellitus (T2DM). However, it is unclear whether this is
Min Jae Cha, Negar Firoozeh, Anna V. Naumova, Peter Muzi, Karen G. Ordovas, Dennis D. Wang, Daniel Isquith, Chuck Maynard, Xue‐Qiao Zhao, Francis Kim   +9 more
wiley   +1 more source

Incretins and their influence on the course of type 2 diabetes in patients with morbid obesity after bariatric oper [PDF]

, 2012
Most researchers support the important role of incretins, particularly glucagon-like peptide-1 in improving metabolic control in patients with type 2 diabetes after bariatric operations, mostly involving shunting.

core   +2 more sources

The use of incretins and fractures - a meta-analysis on population-based real life data [PDF]

, 2017
Item does not contain fulltextThe aim of the present study was to estimate the effect of incretins on fracture risk in the real-world situation by meta-analysis of the available population-based cohort data.
Henry, R.M., Vestergaard, P, Driessen, Johanna H. M., Driessen, J.H., Vestergaard, Peter, Neef, C., Harvey, Nicholas C., van den Bergh, Joop P. W.; id_orcid, Onzenoort, H. van, de Vries, F, Johanna H. M. Driessen, Driessen, J H M, Cees Neef, Henry, R M A, Nicholas C. Harvey, van Onzenoort, H, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, van den Bergh, J, Vries, F de, Frank de Vries, Van den Bergh, Joop, Driessen, Johanna H. M.; id_orcid, Henry, Ronald M. A., Neef, C, Joop P. W. van den Bergh, de Vries, Frank; id_orcid, Peter Vestergaard, Ronald M. A. Henry, van Onzenoort, Hein, Harvey, N.C., Neef, Cees, Hein van Onzenoort, van den Bergh, Joop P. W., Harvey, N C, Bergh, J.P. van den, Vestergaard, P., de Vries, Frank, Vestergaard, P; id_orcid   +38 more
core   +3 more sources

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

The Pharmacologic Exploitation of Pleiotropic Effect of Incretins [PDF]

This thesis aims to explore the various effects of incretins on the many systems of the body and how they can be utilized pharmacologically. It will investigate their use in treatment for diabetes mellitus type 2, which they were initially introduced as ...
Khan, Tazeen
core  

Women with COPD by biomass show different serum profile of adipokines, incretins, and peptide hormones than smokers [PDF]

, 2018
Background The main causes of COPD are tobacco smoking (COPD-TS) and biomass smoke exposure (COPD-BS). COPD-TS is known to induce changes in adipokines, incretins, and peptide hormones, frequent biomarkers of inflammation; however, it is unknown if ...
Yadira Velasco-Torres, Joaquín Zúñiga-Ramos, Tonatiuh Barrientos-Gutiérrez, Martha Montaño, Carlos Ramos, Rogelio Pérez-Padilla, Mariana Camacho-Priego, Oliver Pérez-Bautista, Ivette Buendía-Roldan   +8 more
core   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

Potential Effect of DPP-4 Inhibitors Towards Hepatic Diseases and Associated Glucose Intolerance

Diabetes, Metabolic Syndrome and Obesity, 2022
Ashwani Sharma,1 Tarun Virmani,1 Anjali Sharma,2 Vaishnavi Chhabra,1 Girish Kumar,1 Kamla Pathak,3 Abdulsalam Alhalmi4 1School of Pharmaceutical Sciences, MVN University, Palwal, Haryana, 121105, India; 2Freelancer, Pharmacovigilance Expert, Uttar ...
Sharma A, Virmani T, Sharma A, Chhabra V, Kumar G, Pathak K, Alhalmi A   +6 more
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