Results 71 to 80 of about 8,656 (193)
Therapy in the Early Stage: Incretins
, 2011 The complex pathological mechanisms responsible for development of type 2 diabetes are not fully addressed by conventional drugs, which are also associated with inconvenient side effects such as weight gain or ...
Simona Cernea, Itamar Raz
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Ожирение и метаболизмBACKGROUND: Obesity is a pathology that highly contributes to the development of type 2 diabetes mellitus and cardiovascular diseases. Meanwhile, different obesity phenotypes have varying levels of risk, and the indication of early predictors that can ...
G. A. Matveev +3 more
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Metabolic Connection between Incretins and Pulmonary Hypertension
, 2015 Studies show that at least half the adult population is overweight in most countries. Recent case reports have shown the important metabolic potential of the pathophysiology of PAH.
Silva, Ivan Enokibara da +7 more
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Incretins and diabetes mellitus type 2 - from pathophysiology to therapeutic treatment [PDF]
, 2014 Moderni terapijski pristup liječenju šećerne bolesti tipa 2 usmjeren je na povećanje razine inkretinskih hormona u cirkulaciji. Inkretini su endogeni regulatorni peptidi koje izlučuju stanice crijeva i koji potiču otpuštanje inzulina, inhibiraju ...
Ranđelović, Karla
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, 2002 OBJECTIVE: Although the incretins, gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), as well as glucagon and cortisol, are known to influence islet function, the role of these hormones in conditions of insulin resistance and ...
Forsberg, Hakan +6 more
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Angioprotektivnoe properties lowering drugs from the group of inhibitors of dipeptidyl peptidase-4
Терапевтический архив, 2013 Diabetes mellitus (DM) is a major health problem in all developed countries. It contributes to the development of atherosclerosis and increases the risk of cardiovascular events so blood glucose level correction is essential to preventing these ...
E V Oskola, A T Shubina, Iu A Karpov
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Glucagon-like peptide-1 analogues: An overview
Indian Journal of Endocrinology and Metabolism, 2013 Abnormalities of the incretin axis have been implicated in the pathogenesis of type 2 diabetes mellitus. Glucagon-like peptide-1 (GLP-1) and gastroinhibitory intestinal peptide constitutes >90% of all the incretin function.
Vishal Gupta
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Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins [PDF]
, 2021 A better understanding of GLP-1 and GIP biology, physiology and pathophysiology are currently within the focus of many labs across the world, since they are in the basement of the development of new therapies for treating type 2 Diabetes and obesity ...
Gagliardino, Juan José +1 more
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The Pharmacologic Exploitation of Pleiotropic Effect of Incretins
This thesis aims to explore the various effects of incretins on the many systems of the body and how they can be utilized pharmacologically. It will investigate their use in treatment for diabetes mellitus type 2, which they were initially introduced as ...
Khan, Tazeen
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Endocrine ConnectionsBackground/objectives: Glucose-dependent insulinotropic polypeptide (GIP) is secreted by enteroendocrine K cells in response to nutrient ingestion. The aims of this study were: i) to evaluate the cross-sectional associations between plasma GIP change in ...
Isidora Salvatierra +6 more
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