Results 51 to 60 of about 23,127 (334)

Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus

Сахарный диабет, 2023
Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus© Fatima O. Ushanova1*, Tatiana Y. Demidova1, Tatiana N. Korotkova21Pirogov Russian National Research Medical University, Moscow,
F. O. Ushanova, T. Y. Demidova, T. N. Korotkova   +2 more
doaj   +1 more source

Interplay between bone and incretin hormones: A review [PDF]

, 2017
Bone is a tissue with multiple functions that is built from the molecular to anatomical levels to resist and adapt to mechanical strains. Among all the factors that might control the bone organization, a role for several gut hormones called "incretins ...
G. Mabilleau
core   +4 more sources

Update on incretin hormones [PDF]

Annals of the New York Academy of Sciences, 2011
The incretin hormones glucagon‐like‐peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) are released from the intestine following oral ingestion of nutrients. Incretins promote insulin secretion, while GLP‐1 also inhibits glucagon release and gastric emptying, minimizing postprandial glucose excursions.
Phillips, Liza K., Prins, Johannes B.
openaire   +3 more sources

Modulation of Diabetes by Natural Products and Medicinal Plants via Incretins

Planta Medica, 2019
Incretins are metabolic hormones released after a meal that increase insulin secretion from pancreatic β-cells. The two main incretins are the intestinal peptides glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide.
J. Ríos, I. Andújar, G. Schinella, F. Francini   +3 more
semanticscholar   +1 more source

Brain access of incretins and incretin receptor agonists to their central targets relevant for appetite suppression and weight loss

American Journal of Physiology. Endocrinology and Metabolism
Incretin-based pharmacotherapies provide novel efficient and safe therapeutic options to curb appetite and produce weight loss in obese patients. Delivered systemically, these molecules produce pleiotropic metabolic benefits, but the target sites ...
Sophie Buller, Clémence Blouet
semanticscholar   +1 more source

Incretin-based therapy for the treatment of bone fragility in diabetes mellitus [PDF]

, 2018
Bone fractures are common comorbidities of type 2 diabetes mellitus (T2DM). Bone fracture incidence seems to develop due to increased risk of falls, poor bone quality and/or anti-diabetic medications.
B. Bouvard, B. Gobron, D. Chappard, G. Mabilleau   +3 more
core   +3 more sources

Glucagon-like peptide-1 analogues: An overview

Indian Journal of Endocrinology and Metabolism, 2013
Abnormalities of the incretin axis have been implicated in the pathogenesis of type 2 diabetes mellitus. Glucagon-like peptide-1 (GLP-1) and gastroinhibitory intestinal peptide constitutes >90% of all the incretin function.
Vishal Gupta
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

GLP-1 and GIP in Type 1 Diabetes Therapy: A Time for Reappraisal?

Diabetology
Incretin hormones, such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), are essential regulators of glucose homeostasis, energy balance, and metabolic communication between organs.
Grazia Piras, Sara Brasili, Davide Demontis, Leonardo Della Sala, Francesco Cocchiara, Davide Carlo Maggi, Anna Arecco   +6 more
doaj   +1 more source