1′-Methyl-4′-[4-(trifluoromethyl)phenyl]dispiro[indan-2,2′-pyrrolidine-3′,2′′-indan]-1,3,1′′-trione [PDF]
Dans le composé du titre, C(28)H(20)F(3)NO(3), le cycle pyrrolidine adopte une conformation en demi-chaise. Les autres cycles à cinqchaînonsadoptent des conformations d'enveloppe avec les atomes de spiro et de méthylène C comme atomes de lambeau. Dans le cristal,les mol-éculessont connectées via de faibles liaisonshydrogène C-H O, formant des feuilles ...
Ang Chee Wei +4 more
openaire +4 more sources
(E)-2-(3,5-Dimethoxybenzylidene)indan-1-one [PDF]
The title chalcone, C18H16O3, was prepared by a solventless base-promoted Claisen–Schmidt condensation and, upon recrystallization from ethanol, obtained in 56% yield. The dihedral angle between the indanone ring system and the benzene ring is 2.54 (4) ° and the C atoms of the methoxy groups deviate from the benzene ring by 0.087 (1) and 0.114 (1) Å ...
Elvia Encarnacion-Thomas +3 more
openaire +4 more sources
(E)-2-(4-Chlorobenzylidene)indan-1-one [PDF]
In the title compound, C16H11ClO, the dihedral angle between the almost planar dihydroindene ring system (r.m.s. deviation = 0.009 Å) and the chlorobenzene ring is 3.51 (14) °. In the crystal, mol ecules are connected by C-H? O and weak C-H? Cl interactions, forming infinite layers parallel to (101).
Mohamed Ashraf Ali +4 more
openaire +5 more sources
The rearrangement of beta,gamma-unsaturated esters, such as 2-(3,4-dihydronaphthalen-1-yl)-propionic acid ethyl ester, with thallium trinitrate (TTN) in acetic acid leads to 3-indan-1-yl-2-methyl-3-oxo-propionic acid ethyl ester in good yield, through a ...
Silva Jr. Luiz F. +2 more
doaj +1 more source
Thermal high pressure hydrogenolysis II. The thermal high pressure hydrocracking of fluorene [PDF]
The thermal hydrocracking of fluorene was investigated in the temperature range of 400 to 480 °C and hydrogen pressures of up to 375 atm. As main reaction products were found 2-methylbiphenyl, biphenyl, toluene and benzene.
Konter, Willem A.N. +2 more
core +6 more sources
A new sighting study for the fixed concentration procedure to allow for gender differences [PDF]
The fixed concentration procedure (FCP) has been proposed as an alternative to the median lethal concentration (LC50) test (organisation for economic co-operation and development (OECD) test guideline [TG] 403) for the assessment of acute inhalation ...
Charlotte Price +11 more
core +2 more sources
Computer Aided Aroma Design. II. Quantitative structure-odour relationship [PDF]
Computer Aided Aroma Design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution. The two crucial steps in CAMD are the generation of candidate molecules and the estimation of properties ...
Floquet, Pascal +5 more
core +2 more sources
An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity [PDF]
Acute inhalation studies are conducted in animals as part of chemical hazard identification and for classification and labelling. Current methods employ death as an endpoint (OECD TG403 and TG436) while the recently approved fixed concentration procedure
Griffiths, David +8 more
core +2 more sources
EURL ECVAM strategy to replace, reduce and refine the use of animals in the assessment of acute mammalian systemic toxicity [PDF]
Information on acute systemic toxicity represents a standard requirement within several pieces of chemicals legislation in the EU. One of the main drivers of conducting the test is classification and labelling.
BURTON JULIEN +5 more
core +1 more source
N‐Insertion of Diazonium Salts Into Ketone Derivatives
Diazonium salts insert into ketones and their silyl enol ethers through a sequence of α‐azenylation and ring expansion via an N‐iminoaziridinium species. Coupled with an efficient N‐N bond cleavage, this protocol offers a mild alternative to Beckmann rearrangements and a powerful tool for skeletal editing of ketones.
Mohammed Anif Pasha +3 more
wiley +2 more sources

