Results 81 to 90 of about 10,572 (203)

PIIIPV═O Redox‐Catalyzed Direct Amide‐to‐Ketimine Transformation via Friedel–Crafts‐type C─C Bond Formation

open access: yesChemCatChem, Volume 18, Issue 4, 25 February 2026.
A series of ketimines were synthesized via electrophilic aromatic substitution on indole and pyrrole derivatives. This synthetic method is based on activating amides using PIII/PV═O redox catalysis, yielding an imidoyl chloride intermediate. Subsequent conversion with indole and pyrrole derivatives afforded 20 novel ketimines in yields up to 94 ...
Viktorija Medvarić   +2 more
wiley   +1 more source

1-(4-Methylphenylsulfonyl)-5,6-dinitro-1H-indazole

open access: yesActa Crystallographica Section E, 2014
In the title compound, C14H10N4O6S, the indazole ring system is almost perpendicular to the tosyl ring, as indicated by the dihedral angle of 89.40 (9)° between their planes.
Bassou Oulemda   +4 more
doaj   +1 more source

Crystal Structure of 4,6-dinitro-1-(5-tetrazolyl)-1H-indazole Trihydrate [PDF]

open access: yes, 1984
The title compound, C8H4N8O4·3H2O, crystallizes in space groupP¯1 with cell constantsa=7.022(1),b=9.507(2),c=10.906(2) Å,α=84.99(1),β=71.89(1),γ=72.56(1)°,Z=2, andV c =660.2 Å3. The structure was solved by direct methods using diffractometer data and was
Puttaraja, .   +2 more
core   +1 more source

Recent Contributions of Organic Synthesis to Forensic Science

open access: yesChemPlusChem, Volume 91, Issue 2, February 2026.
Forensic science is a multidisciplinary field that plays a vital role in providing scientific evidence for criminal investigations. This review highlights advances and opportunities at the interface between organic synthesis and forensic science, with applications in drug identification, forensic toxicology, and latent fingerprint detection and ...
Gustavo dos Santos Martins   +3 more
wiley   +1 more source

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

open access: yesDrug Testing and Analysis, Volume 18, Issue 2, Page 198-206, February 2026.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner   +4 more
wiley   +1 more source

Synthesis, Characterization, In-silico and Biological Evaluation of Indazole Derivatives as Potential Anti-Inflammatory and Antimicrobial Agents

open access: yesRGUHS Journal of Pharmaceutical Sciences
Introduction Indazoles also known as isoindazone or benzpyrazole are fused bicyclic heteroaromatic organic molecules with a wide range of biological activities.
Hanamant B Sannakki   +6 more
doaj   +1 more source

Metal‐Organic Framework/Organocatalyst Combinations as Powerful Multicatalytic Systems for Aerobic Oxidations

open access: yesAngewandte Chemie, Volume 138, Issue 3, 16 January 2026.
A multicatalytic strategy based on the simple combination of metal‐organic frameworks (MOFs) and organocatalysts is able to mediate challenging aerobic oxidation reactions. The use of earth‐abundant MOFs and commercially available (hydro)quinone co‐catalysts greatly simplify the generation of powerful multicatalytic systems, opening the door for the ...
Juan Camilo Arango‐Daza   +5 more
wiley   +1 more source

2,2′-(Propane-1,3-diyl)bis(2H-indazole)

open access: yesActa Crystallographica Section E, 2011
The title molecule, C17H16N4, is a bis-indazole crystallized in the rare 2H-tautomeric form. Indazole heterocycles are connected by a propane C3 chain, and the molecule is placed on a general position, in contrast to the analogous compound with a central
Saúl Ovalle   +3 more
doaj   +1 more source

Redox activation of metal-based prodrugs as a strategy for drug delivery [PDF]

open access: yes, 2011
This review provides an overview of metal-based anticancer drugs and drug candidates. In particular, we focus on metal complexes that can be activated in the reducing environment of cancer cells, thus serving as prodrugs. There are many reports of Pt and
Graf, Nora, Lippard, Stephen J.
core   +1 more source

Design, Synthesis, and Evaluation of EA-Sulfonamides and Indazole-Sulfonamides as Promising Anticancer Agents: Molecular Docking, ADME Prediction, and Molecular Dynamics Simulations

open access: yesChemistry
New EA-sulfonamides and indazole-sulfonamides were synthesized, characterized, and evaluated for their anticancer activities. The target compound structures were elucidated using various spectroscopic techniques such as NMR-{1H and 13C}, infrared ...
Nassima Saghdani   +6 more
doaj   +1 more source

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