Results 91 to 100 of about 4,425 (285)

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

The Effectiveness of Giving Direct and Indirect Corrective Feedback on Eighth Graders' Recount Compositions

open access: yes, 2016
Sari, Najwa Kumala. 2016. The Effectiveness of Giving Direct and Indirect Corrective feedback on Eighth Graders’ Recount Compositions. Sarjana’s Thesis, English Department, Faculty of Letters, State University of Malang. Advisors: (I) Dr.
Najwa Kumala Sari; Mahasiswa
core  

Investigating Teachers and Students’ Perceptions of Written Corrective Feedback in the Context of Tertiary Education in Oman [PDF]

open access: yes, 2019
This paper focuses on written corrective feedback in the testing context of the English language foundation program at Sultan Qaboos University in Oman. In more detail, in response to the encountered testing problem that involves  ...
Farah Bahrouni,Victoria Tuzlukova
core   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

The effectiveness of comprehensive corrective feedback-direct and indirect- on EFL learners' language accuracy, structural complexity and lexical diversity [PDF]

open access: yes, 2019
This study investigates the effectiveness of direct and indirect written corrective feedback in improving EFL learners' written language accuracy, complexity and lexical diversity. It also examines the students' strategies in dealing with feedback.
Dabboub, AE
core  

Providing Indirect Corrective Feedback: a Technique to Reduce Errors in Students' Writing [PDF]

open access: yes, 2016
This experimental study aims at investigating the application of Indirect Corrective Feedback (ICF) in teaching writing recount text. The subjects of the study were tenth graders of SMAN 1 Meulaboh who are chosen randomly.
Samad, Iskandar Abdul   +5 more
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Effects of Two Types of Indirect Written Corrective Feedback on the Acquisition of English Articles

open access: yesForeign Languages Education, 2017
The study investigates the relative effects of two types of indirect written corrective feedback (CF) on the acquisition of English articles. Thirty-five high intermediate Korean EFL college students who were enrolled in three composition classes participated in this study.
Mijeong Song, Given Lee
openaire   +1 more source

The Comparative Effect of Direct and Indirect Corrective Feedback in Process-Based Vs. Product-Based Writing Instruction on EFL Learners` Writing Performance [PDF]

open access: yesJournal of Applied Linguistics, 2016
This study attempted to systematically inspect the impact of direct and indirect corrective feedbacks on the writing ability of EFL learners when using product/process based instructions.
Neda Osanloo, Sholeh Kolahi
doaj  

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

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