Results 61 to 70 of about 1,841,652 (284)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The Comparative Effect of Direct and Indirect Corrective Feedback in Process-Based Vs. Product-Based Writing Instruction on EFL Learners` Writing Performance [PDF]
Journal of Applied Linguistics, 2016 This study attempted to systematically inspect the impact of direct and indirect corrective feedbacks on the writing ability of EFL learners when using product/process based instructions.
Neda Osanloo, Sholeh Kolahi
doaj
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The impact of direct and indirect error treatment on student writing accuracy [PDF]
Teaching English Language, 2011 The present study investigates whether the type of feedback (direct or indirect) given to 41 intermediate EFL learners on six types of errors (verb tense, noun ending, word choice, sentence structure, article and preposition) results in improved accuracy
Masood Khalili Sabet +2 more
doaj +1 more source
Direct vs Indirect Written Corrective Feedback: An Action Research
Trakya Eğitim Dergisi, 2020 The aim of the present study was to find out if direct or indirect written corrective feedback was more beneficial for a group of 28 students in the English Prep Year of an engineering department at a public university in Turkey. Utilizing an action research design, the observation and reflection phases of the study included the observation of the ...
Kutay UZUN, Handan KÖKSAL
openaire +3 more sources
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
The Impact of Indirect Feedback on Learning Writing
Issues in Language Instruction, 2018 Correction of writing errors in the classroom requires much time and work from the instructor. A learner-centered approach helps students notice and correct their own errors. This presentation offers instructors techniques to give students indirect feedback, and reviews the major influences on the acquisition of writing skills.
openaire +2 more sources
The Effect of Direct and Indirect Corrective Feedback on L2 Learners’ Written Accuracy [PDF]
ITL - International Journal of Applied Linguistics, 2008 Abstract Among scholars there is disagreement on the benefits of corrective feedback on second language learners’ written output. While some researchers advocate the usefulness of corrective feedback, Truscott claims that all error correction is unnecessary, ineffective, and even harmful, in that it diverts time and energy away from
Catherine van Beuningen +2 more
openaire +2 more sources
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Delayed onset of positive feedback activation of Rab5 by Rabex-5 and Rabaptin-5 in endocytosis. [PDF]
PLoS ONE, 2010 Rabex-5 is a guanine nucleotide exchange factor (GEF) that specifically activates Rab5, i.e., converting Rab5-GDP to Rab5-GTP, through two distinct pathways to promote endosome fusion and endocytosis.
Huaiping Zhu, Hong Qian, Guangpu Li
doaj +1 more source