Results 161 to 170 of about 4,853 (196)

Metagenomic and metabolite analysis reveals microbial community and metabolite dynamics in fermented Indigo naturalis. [PDF]

Heliyon
Yuan X, Zhang D, Li D, Ji Q, Gao J, Hou F, Chen Y.   +6 more
europepmc   +1 more source

Discovery of Antimicrobial Oligoindoles from a Cold-Seep-Derived Halomonas Strain. [PDF]

Mar Drugs
Yan Y, Li Z, Li H, Sun J, Li W, Xiao F.
europepmc   +1 more source

Computational discovery of novel aryl hydrocarbon receptor modulators for psoriasis therapy. [PDF]

Sci Rep
Santini G, Bonati L, Motta S.
europepmc   +1 more source

Natural Alkaloids as Antiviral Agents Against RNA Viruses: A Comprehensive and Mechanistic Review. [PDF]

Molecules
Leka K, Mamede L, Vandeberg E, Garigliany MM, Ledoux A.   +4 more
europepmc   +1 more source

Indigo naturalis for inflammatory bowel disease: evidence from animal studies and molecular mechanisms. [PDF]

Front Pharmacol
Hu J, Zhou M, Huang L, Guo X, Mei P, Li P, Wang Y, Chen Y.   +7 more
europepmc   +1 more source

A new 1,2,3-triazole-indirubin hybrid suppresses tumor growth and pulmonary metastasis by mitigating the HGF/c-MET axis in hepatocellular carcinoma. [PDF]

J Adv Res
Gowda SV, Kim NY, Harsha KB, Gowda D, Suresh RN, Deivasigamani A, Mohan CD, Hui KM, Sethi G, Ahn KS, Rangappa KS.   +10 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Synthesis and activity of novel indirubin derivatives

Chemical Biology & Drug Design, 2020
AbstractA series of indirubin derivatives hydrochloride were obtained using a convenient and mild method from indirubin. The newly synthesized compounds and their derivatives were characterized by 1H NMR, 13C NMR, and MS. Furthermore, we tested their IDO1 enzyme inhibitory activity and anti‐proliferative activities in K562 tumor cells. The experimental
Bin, Sun, Jiahao, Wang, Luohua, Liu, Longfei, Mao, Lizeng, Peng, Yuwei, Wang   +5 more
openaire   +2 more sources

Indirubin derivatives inhibit malignant lymphoid cell proliferation

Leukemia & Lymphoma, 2009
Indirubin-3'-monoxime (IO) is a derivative of indirubin, an active compound of a traditional Chinese medicinal recipe used to treat various inflammatory and malignant diseases. The main in vitro targets of IO (i.e. cyclin dependent kinases, glycogen synthase kinase-3beta, Stat 3 and Aryl hydrocarbon receptor) are regulators of lymphocyte activation. We
Amel, Chebel, Sandrine, Kagialis-Girard, Regine, Catallo, Wei Wen, Chien, Valérie, Mialou, Carine, Domenech, Cedric, Badiou, Isabelle, Tigaud, Martine, Ffrench   +8 more
openaire   +2 more sources

Developing synthetic microbes to produce indirubin-derivatives

Biocatalysis and Agricultural Biotechnology, 2021
Abstract Indirubins are natural-plant secondary metabolites that belong to the family of indigoids. Indirubin and its derivatives play a vital role in the fields of dyes and medicinal chemistry. Indirubin is an active ingredient of traditional Chinese medicine that is used to treat chronic myeloid leukemia.
Sandipty Kayastha, Laxmi Sagwan-Barkdoll, Aldwin Anterola, Lahiru N. Jayakody   +3 more
openaire   +1 more source

Indirubin inhibits inflammatory reactions in delayed-type hypersensitivity

European Journal of Pharmacology, 2000
Polygonum tinctorium Lour. (P. tinctorium) is known to have the ability to suppress inflammation. We attempted to isolate the active compounds from P. tinctorium based on their inhibitory effects on the production of interferon-gamma, which is a well-known inflammatory cytokine. We thus isolated indirubin, an isomer of indigo.
T, Kunikata, T, Tatefuji, H, Aga, K, Iwaki, M, Ikeda, M, Kurimoto   +5 more
openaire   +2 more sources