Results 31 to 40 of about 9,369 (148)

Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand.

PLoS ONE, 2020
Indole-3-acetic acid (IAA) is an imperative phytohormone for plant growth and development. Ectomycorrhizal fungi (ECM) are able to produce IAA. However, only a few studies on IAA biosynthesis pathways in ECM fungi have been reported.
Jaturong Kumla, Nakarin Suwannarach, Kenji Matsui, Saisamorn Lumyong   +3 more
doaj   +1 more source

Determination of Tryptophan Metabolites in Serum and Cerebrospinal Fluid Samples Using Microextraction by Packed Sorbent, Silylation and GC–MS Detection

Molecules, 2020
Indole-containing acids—tryptophan metabolites—found in serum and cerebrospinal fluid (CSF) samples of patients with diseases of the central nervous system (CNS) were determined with the use of microextraction by packed sorbent (MEPS) followed by ...
Alisa Pautova, Zoya Khesina, Maria Getsina, Pavel Sobolev, Alexander Revelsky, Natalia Beloborodova   +5 more
doaj   +1 more source

Dose-Dependent Beneficial Effects of Tryptophan and Its Derived Metabolites on Akkermansia In Vitro: A Preliminary Prospective Study

Microorganisms, 2021
Akkermansia muciniphila, a potential probiotic, has been proven to lessen the effects of several diseases. As established, the relative abundance of Akkermansia is positively correlated with tryptophan metabolism.
Jia Yin, Yujie Song, Yaozhong Hu, Yuanyifei Wang, Bowei Zhang, Jin Wang, Xuemeng Ji, Shuo Wang   +7 more
doaj   +1 more source

Characterization of indole-3-pyruvic acid pathway-mediated biosynthesis of auxin in Neurospora crassa. [PDF]

PLoS ONE, 2018
Plants, bacteria and some fungi are known to produce indole-3-acetic acid (IAA) by employing various pathways. Among these pathways, the indole-3-pyruvic acid (IPA) pathway is the best studied in green plants and plant-associated beneficial microbes ...
Puspendu Sardar, Frank Kempken
doaj   +1 more source

Microbial metabolites indole derivatives sensitize mice to D-GalN/LPS induced-acute liver failure via the Tlr2/NF-κB pathway

Frontiers in Microbiology, 2023
IntroductionAcute liver failure (ALF) is a clinical condition with many causes, fast progression, and a poor prognosis. Previous research has indicated that microbial factors have a role in ALF, but a clear picture has yet to emerge.MethodsTo investigate
Ziyuan Zhou, Baohong Wang, Xiaxia Pan, Jiawen Lv, Zhuoqi Lou, Yuqiu Han, Yuanyuan Yao, Jun Chen, Qiangqiang Wang, Lanjuan Li   +9 more
doaj   +1 more source

Production of Hydroxycarboxylic Acid Receptor 3 (HCA₃) Ligands by Bifidobacterium

Microorganisms, 2021
Hydroxycarboxylic acid receptor 3 (HCA3) was recently identified in the genomes of humans and other hominids but not in other mammals. We examined the production of HCA3 ligands by Bifidobacterium spp.
Takuma Sakurai, Ayako Horigome, Toshitaka Odamaki, Takashi Shimizu, Jin-Zhong Xiao   +4 more
doaj   +1 more source

UPLC-QTOF-MS/MS and GC-MS Characterization of Phytochemicals in Vegetable Juice Fermented Using Lactic Acid Bacteria from Kimchi and Their Antioxidant Potential

Antioxidants, 2021
This study aims to investigate fermentative metabolites in probiotic vegetable juice from four crop varieties (Brassica oleracea var. capitata, B. oleracea var. italica, Daucus carota L., and Beta vulgaris) and their antioxidant properties.
Moeun Lee, Jung Hee Song, Eun Ji Choi, Ye-Rang Yun, Ki Won Lee, Ji Yoon Chang   +5 more
doaj   +1 more source

The role of bacterial metabolites derived from aromatic amino acids in non-alcoholic fatty liver disease

Alʹmanah Kliničeskoj Mediciny, 2020
The review deals with the role of aromatic amino acids and their microbial metabolites in the development and progression of non-alcoholic fatty liver disease (NAFLD).
E. S. Shcherbakova, T. S. Sall, S. I. Sitkin, T. Ya. Vakhitov, E. V. Demyanova   +4 more
doaj   +1 more source

Pharmacokinetic Properties of the Novel Synthetic Cannabinoid 5F-APINAC and Its Influence on Metabolites Associated with Neurotransmission in Rabbit Plasma

Pharmaceuticals, 2021
The strong psychoactive effects of synthetic cannabinoids raise the need for the deeper studying of their neurometabolic effects. The pharmacokinetic properties of 5F-APINAC and its influence on metabolomics profiles associated with neurotransmission ...
Ksenia M. Shestakova, Natalia V. Mesonzhnik, Pavel A. Markin, Natalia E. Moskaleva, Andrey A. Nedorubov, Alex Brito, Elizaveta G. Appolonova, Roman M. Kuznetsov, Natalia L. Bochkareva, Alexey Kukharenko, Alexey V. Lyundup, Franco Tagliaro, Svetlana A. Appolonova   +12 more
doaj   +1 more source

The role of microbial indole metabolites in tumor

Gut Microbes
The gut microbiota can produce a variety of microbial-derived metabolites to influence tumor development. Tryptophan, an essential amino acid in the human body, can be converted by microorganisms via the indole pathway to indole metabolites such as ...
Dingjiacheng Jia, Zheng Kuang, Liangjing Wang   +2 more
doaj   +1 more source