Results 41 to 50 of about 487,159 (190)

Sorafenib versus Lenvatinib Causes Stronger Oxidative Damage to Membrane Lipids in Noncancerous Tissues of the Thyroid, Liver, and Kidney: Effective Protection by Melatonin and Indole-3-Propionic Acid

Biomedicines, 2022
Sorafenib and lenvatinib are multi-targeted tyrosine kinase inhibitors which are currently approved to treat advanced hepatocellular carcinoma, renal cell carcinoma and radioiodine-refractory differentiated thyroid carcinoma.
Jan Stępniak, Joanna Krawczyk-Lipiec, Andrzej Lewiński, Małgorzata Karbownik-Lewińska   +3 more
doaj   +1 more source

Susceptibility of Legionella pneumophila grown extracellularly and in human monocytes to indole-3-propionic acid [PDF]

Antimicrobial Agents and Chemotherapy, 1991
Indole-3-propionic acid (IPA), a phytohormone derivative, is a potent inhibitor of growth of Legionella pneumophila cultivated extracellularly in a chemically defined hypotonic medium and intracellularly in human monocytes. The inhibitory activity turns into bactericidal activity with increasing concentrations.
F, Mandelbaum-Shavit, V, Barak, K, Saheb-Tamimi, N, Grossowicz   +3 more
openaire   +2 more sources

Response of pine hypocotyl sections to growth regulators and related substances

Acta Societatis Botanicorum Poloniae, 2015
Growth response of Pinus silvestris hypocotyl sections to some synthetic growth regulators and related substances was studied. Elongation of hypocotyl sections was stimulated by naphtaleneacetic acid, indole-3-acetic acid, in-dole-3-propionic acid ...
J. Zakrzewski
doaj   +1 more source

Synthesis, Characterization and Antibacterial Activity Evaluation of New Indole-Based Derivatives

Iraqi Journal of Pharmaceutical Sciences, 2020
A new series of N-acyl hydrazones (4a-g) derived from indole-3-propionic acid (IPA) were synthesized. These N-acyl hydrazones were prepared by the reaction of 3-(1H-indol-3-yl) propane hydrazide and aldehyde in the existence of glacial acetic acid as a ...
Ahmed T. Sulaiman, Susan W. Sarsam
doaj   +1 more source

MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of liver transplantation [PDF]

, 2011
Background: Propionic acidaemia (PA) results from deficiency of Propionyl CoA carboxylase, the commonest form presenting in the neonatal period. Despite best current management, PA is associated with severe neurological sequelae, in particular movement ...
Peet Andrew C, Patrick J McKiernan, Davison, JE, Wilson, M, John H Walter, Walter John H, P Gissen, Davies, Nigel, Yu Sun, Gissen P, Peet, Andrew, Chakrapani, A, Davison James E, Martin Wilson, James E Davison, Peet, AC, Davies, NP, McKiernan, PJ, Wilson Martin, Andrew C Peet, Davies Nigel P, Wilson, Martin; id_orcid, McKiernan Patrick J, Nigel P Davies, Gissen, P, Sun Yu, Anupam Chakrapani, Gissen, Paul, Walter, JH, Chakrapani Anupam, Davison, James, Sun, Y, McKiernan, Patrick   +32 more
core   +1 more source

Determination of Tryptophan Metabolites in Serum and Cerebrospinal Fluid Samples Using Microextraction by Packed Sorbent, Silylation and GC–MS Detection

Molecules, 2020
Indole-containing acids—tryptophan metabolites—found in serum and cerebrospinal fluid (CSF) samples of patients with diseases of the central nervous system (CNS) were determined with the use of microextraction by packed sorbent (MEPS) followed by ...
Alisa Pautova, Zoya Khesina, Maria Getsina, Pavel Sobolev, Alexander Revelsky, Natalia Beloborodova   +5 more
doaj   +1 more source

The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis

Cellular and Molecular Gastroenterology and Hepatology, 2023
Fibrosis is a common complication of inflammatory bowel diseases (IBDs). The pregnane X receptor (PXR) (encoded by NR1I2) suppresses intestinal inflammation and has been shown to influence liver fibrosis. In the intestine, PXR signaling is influenced by microbiota-derived indole-3-propionic acid (IPA).
Kyle L. Flannigan, Kristoff M. Nieves, Holly E. Szczepanski, Alex Serra, Joshua W. Lee, Laurie A. Alston, Hena Ramay, Sridhar Mani, Simon A. Hirota   +8 more
openaire   +3 more sources

Effect of propionic acid on Campylobacter jejuni attached to chicken skin during refrigerated storage [PDF]

, 2015
The ability of propionic acid to reduce Campylobacter jejuni on chicken legs was evaluated. Chicken legs were inoculated with Campylobacter jejuni. After dipping legs in either water (control), 1% or 2% propionic acid solution (vol/vol), they were stored
González Fandos, Elena [0000-0002-9500-5343], Pérez Arnedo, Iratxe [0000-0001-7053-1024], Maya Zumeta, Naiara   +2 more
core   +1 more source

Single‐Atom Iron‐Catalyzed Oxidative Esterification: From Methylarenes to the Upcycling of Polystyrene and Lignin‐Derived Feedstocks

Angewandte Chemie, EarlyView.
Heterogeneous iron‐catalyzed environmentally benign and sustainable CH‐oxidative esterification methodology has been developed for the synthesis of esters. This challenging reaction has been achieved by the rational design of specific single atom iron‐based catalyst with Fe‐N4 active centers, which empowered the oxidative esterification of methyl and ...
Zhuang Ma, Binyu Zhang, Hui Yang, Yue Hu, Junzheng Yu, Yanbin Cui, Jun Zhao, Matthias Beller, Rajenahally V. Jagadeesh   +8 more
wiley   +2 more sources

Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice

mSystems, 2022
Sepsis-associated encephalopathy (SAE) is common in septic patients and is associated with adverse outcomes. The gut microbiota has been recognized as a key mediator of neurological disease development.
Heng Fang, Yirong Wang, Jia Deng, Huidan Zhang, Qingrui Wu, Linling He, Jing Xu, Xin Shao, Xin Ouyang, Zhimei He, Qiuping Zhou, Huifang Wang, Yiyu Deng, Chunbo Chen   +13 more
doaj   +1 more source