Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen
Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
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Recent progress in chemistry and bioactivity of monoterpenoid indole alkaloids from the genus gelsemium: a comprehensive review. [PDF]
J Enzyme Inhib Med Chem, 2023 Wang L +6 more
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Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
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Studies on the phase I and II metabolism and the toxicological analysis of the alkaloids of the herbal drug of abuse Mitragyna speciosa Korth. (Kratom) using gas chromatography-mass spectrometry and liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry [PDF]
, 2011 In the presented studies, the herbal drug Kratom (Mitragyna speciosa) was investigated regarding its metabolism and its toxicological analysis in rat and human urine.
Philipp, Anika-Anina
core
Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares +4 more
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Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales. [PDF]
Fungal Biol Biotechnol, 2023 Rassbach J +9 more
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Chemical Reactions of Indole Alkaloids That Enable Rapid Access to New Scaffolds for Discovery. [PDF]
SynOpen, 2023 Leas DA, Schultz DC, Huigens RW.
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Total Synthesis of the Cyanobacterial Alkaloid Nostodione A
European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.The total synthesis of the alkaloid nostodione A is successfully achieved utilizing 3,4‐dihydrocyclopenta[b]indole‐1,2‐dione as a key intermediate. The sensitive benzylidene moiety is introduced via a Knoevenagel condensation with p‐hydroxybenzaldehyde.
Oscar F. Casadiego‐Díaz +3 more
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The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids. [PDF]
Commun Biol, 2023 Stander EA +22 more
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Structure Revision of Anti-Inflammatory Indole Alkaloids with a 1,2-Benzisoxazole Ring. [PDF]
ACS Omega, 2023 Lee JR, Park KJ, Ham SL, Kim J, Kim CS.
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