Results 1 to 10 of about 50 (46)
Pluripotency of induced pluripotent stem cells [PDF]
Journal of Animal Science and Biotechnology, 2012 Recent studies have demonstrated that differentiated somatic cells from various mammalian species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic expression of four transcription factors that are highly expressed in embryonic stem (ES) cells.
Shaorong Gao, Lan Kang
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Induced pluripotent stem cells are induced pluripotent stem cell-like cells [PDF]
The Journal of Biomedical Research, 2015 Gold is rare and precious, while pyrite (FeS2) is abundant and cheap. Pyrite is nicknamed fool's gold, since pyrite looks like gold and it is even shinier and brighter than gold. It is very difficult to recognize the differences between a real natural gold and a gold-like rock (pyrite) to non-professional persons[1], but we know that all that glitters ...
Emanuel Goldman, Liting Song
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Induced Pluripotent Stem Cells and Hormesis [PDF]
Dose-Response, 2022 This paper represents the first assessment of agent-induced hormetic dose responses in induced pluripotent stem cells and their derived cells. The hormetic dose responses were induced by a broad range of chemicals, including pharmaceuticals (eg, metformin), dietary supplements/extracts from medicinal plants (eg, curcumin), and endogenous agents (eg ...
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Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells [PDF]
World Journal of Stem Cells, 2021 Mesenchymal stem cells (MSCs) have received significant attention in recent years due to their large potential for cell therapy. Indeed, they secrete a wide variety of immunomodulatory factors of interest for the treatment of immune-related disorders and inflammatory diseases. MSCs can be extracted from multiple tissues of the human body.
Dupuis, Victoria +1 more
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Chromatin structure of pluripotent stem cells and induced pluripotent stem cells [PDF]
Briefings in Functional Genomics, 2011 Pluripotent embryonic stem (ES) cells are specialized cells with a dynamic chromatin structure, which is intimately connected with their pluripotency and physiology. In recent years somatic cells have been reprogrammed to a pluripotent state through over-expression of a defined set of transcription factors.
Paul Delgado-Olguin +1 more
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Transgene Reactivation in Induced Pluripotent Stem Cell Derivatives and Reversion to Pluripotency of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells [PDF]
Stem Cells and Development, 2016 Induced pluripotent stem cells (iPSCs) have enormous potential in regenerative medicine and disease modeling. It is now felt that clinical trials should be performed with iPSCs derived with nonintegrative constructs. Numerous studies, however, including those describing disease models, are still being published using cells derived from iPSCs generated ...
Mariana Perepitchka +5 more
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Immunogenicity of Induced Pluripotent Stem Cells [PDF]
Circulation Research, 2011 ### Immunogenicity of Induced Pluripotent Stem Cells Zhao et al Nature . 2011. doi:10.1038/nature10135 A new study shows the immunogenicity of induced pluripotent stem cells by the direct transplantation of undifferentiated cells into syngenic mice.
Shinya Yamanaka +2 more
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Pluripotency of Induced Pluripotent Stem Cells
Genomics, Proteomics & Bioinformatics, 2013 Abstract Induced pluripotent stem (iPS) cells can be generated by forced expression of four pluripotency factors in somatic cells. This has received much attention in recent years since it may offer us a promising donor cell source for cell transplantation therapy. There has been great progress in iPS cell research in the past few years.
Chunjing Feng, Yundan Jia, Xiaoyang Zhao
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An introduction to induced pluripotent stem cells [PDF]
British Journal of Haematology, 2010 SummaryRecent landmark studies show that it is now possible to convert somatic cells, such as skin fibroblasts and B lymphocytes, into pluripotent stem cells that closely resemble embryonic stem cells. These induced pluripotent stem (iPS) cells can be generated without using human embryos or oocytes, thus bypassing some of the ethical issues that have ...
Joanna Hanley +2 more
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The Role of E3s in Regulating Pluripotency of Embryonic Stem Cells and Induced Pluripotent Stem Cells [PDF]
International Journal of Molecular Sciences, 2021 Pluripotent embryonic stem cells (ESCs) are derived from early embryos and can differentiate into any type of cells in living organisms. Induced pluripotent stem cells (iPSCs) resemble ESCs, both of which serve as excellent sources to study early embryonic development and realize cell replacement therapies for age-related degenerative diseases and ...
Yahong Wu, Weiwei Zhang
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