Results 251 to 260 of about 227,684 (338)

Application of induced pluripotent stem cells in the conservation of endangered animals. [PDF]

Stem Cell Res Ther
Lou J, Li W, Chen P, Chen H, Shakoor A, Chen Y, Hua J, Wang Y, Zhang S.   +8 more
europepmc   +1 more source

Deriving an Induced Pluripotent Stem Cell Model of Acute Myeloid Leukemia to Capture and Isolate Disease Heterogeneity

, 2019
Golubeva, Diana
openalex   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Corrigendum for Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins. [PDF]

J Clin Invest
Mo J, Anastasaki C, Chen Z, Shipman T, Papke J, Yin K, Gutmann DH, Le LQ.   +7 more
europepmc   +1 more source

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

Modeling rare genetic disease with gene-edited induced pluripotent stem cells: relevance of the starting stock line. [PDF]

Stem Cells Transl Med
Dinasarapu AR, Sutcliffe DJ, Ozel E, Thite A, Grychowski L, Visser JE, Hess EJ, Kolk SM, Jinnah HA.   +8 more
europepmc   +1 more source

Modeling Choroideremia Disease with Isogenic Induced Pluripotent Stem Cells

Ana Fragoso Fonseca, Rita Coelho, Mafalda Lopes- da-Silva, Luísa de Lemos, Michael J. Hall, Daniela Oliveira, Ana S. Falcão, Sandra Tenreiro, Miguel C. Seabra, Pedro Antas   +9 more
openalex   +2 more sources

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Development of 10 L mass culture system of human induced pluripotent stem cells with intermittent agitation using plastic fluid. [PDF]

Front Bioeng Biotechnol
Tokura T, Yamamoto R, Kino-Oka M.
europepmc   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

Biotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen, Gabriella Faircloth, Nicole T. Marguerite, Mariachiara Conti, Ethan S. Lippmann, Jamey D. Young   +5 more
wiley   +1 more source