Results 11 to 20 of about 4,786,356 (294)
Brassinosteroids-Induced Systemic Stress Tolerance was Associated with Increased Transcripts of Several Defence-Related Genes in the Phloem in Cucumis sativus. [PDF]
Brassinosteroids (BRs), a group of naturally occurring plant steroidal compounds, are essential for plant growth, development and stress tolerance. Recent studies showed that BRs could induce systemic tolerance to biotic and abiotic stresses; however ...
Pingfang Li +6 more
doaj +1 more source
Cellular Tolerance Induced by Chronic Opioids in the Central Nervous System
Opioids are powerful analgesics that elicit acute antinociceptive effects through their action the mu opioid receptor (MOR). However opioids are ineffective for chronic pain management, in part because continuous activation of MORs induces adaptive changes at the receptor level and downstream signaling molecules. These adaptations include a decrease in
Sweta Adhikary, John T. Williams
openaire +3 more sources
This study assessed the potential of Bacillus endophyticus PB3, Bacillus altitudinis PB46, and Bacillus megaterium PB50 to induce drought tolerance in a susceptible rice cultivar.
Arun Kumar Devarajan +7 more
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Long term impact of systemic bacterial infection on the cerebral vasculature and microglia [PDF]
Background: Systemic infection leads to generation of inflammatory mediators that result in metabolic and behavioural changes. Repeated or chronic systemic inflammation leads to a state of innate immune tolerance: a protective mechanism against over ...
Perry, V. Hugh +11 more
core +3 more sources
Plant growth-promoting bacteria (PGPB) can effectively reduce salt damage in plants. Currently, there are many studies on the effects of PGPB on the microbial community structure of rhizosphere soil under salt stress, but fewer studies on the community ...
Chao Ji +17 more
doaj +1 more source
In arid regions, starchy agricultural products such as wheat and rice provide essential carbohydrates, minerals, fibers and vitamins. However, drought, desiccation, high salinity, potentially toxic metals and hydrocarbon accumulation are among the most ...
Abdelwahab Rai +7 more
doaj +1 more source
Engineering human spinal microphysiological systems to model opioid-induced tolerance
Abstract Opioids are commonly used for treating chronic pain. However, with continued use, they may induce tolerance and/or hyperalgesia, which limits therapeutic efficacy. The human mechanisms of opioid-induced hyperalgesia are significantly understudied, in part, because current models cannot fully recapitulate human pathology.
Hongwei Cai +9 more
openaire +3 more sources
Involvement of kappa/dynorphin system in the development of tolerance to nicotine‐induced antinociception [PDF]
AbstractThe aim of the present study was to explore the possible role of kappa/dynorphin system in the development of tolerance to nicotine antinociception in mice. First, we observed that kappa‐opioid receptor (KOP‐r) participates in the acute spinal antinociception produced by nicotine (3 and 5 mg/kg, s.c.) since the pre‐treatment with the selective ...
Lola, Galeote +2 more
openaire +2 more sources
Azospirillum: benefits that go far beyond biological nitrogen fixation
The genus Azospirillum comprises plant-growth-promoting bacteria (PGPB), which have been broadly studied. The benefits to plants by inoculation with Azospirillum have been primarily attributed to its capacity to fix atmospheric nitrogen, but also to its ...
Josiane Fukami +2 more
doaj +1 more source
Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes [PDF]
Abstract Background The maternal immune system needs to tolerate the semi-allogeneic fetus in pregnancy. The adaptation occurs locally at the maternal–fetal interface as well as systemically through the maternal circulation.
Kunfeng Bai +14 more
openaire +3 more sources

