Results 21 to 30 of about 5,003,944 (244)
Frontiers in Pharmacology, 2022 Opioid tolerance, opioid-induced hyperalgesia during repeated opioid administration, and chronic pain are associated with upregulation of adenylyl cyclase activity.
Kayla Johnson +8 more
doaj +1 more source
Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes [PDF]
Journal of Nanobiotechnology, 2022 Abstract Background The maternal immune system needs to tolerate the semi-allogeneic fetus in pregnancy. The adaptation occurs locally at the maternal–fetal interface as well as systemically through the maternal circulation.
Kunfeng Bai +14 more
openaire +3 more sources
Sertoli Cells Induce Systemic Donor-Specific Tolerance in Xenogenic Transplantation Model [PDF]
Cell Transplantation, 2006 Cell therapy is a potentially powerful tool in the treatment of many grave disorders including leukemia, immune deficiencies, autoimmune diseases, and diabetes. However, finding matched donors is challenging and recipients may suffer from the severe complications of systemic immune suppression.
R. Shamekh +5 more
openaire +3 more sources
Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion [PDF]
, 2008 B cells have been shown in various animal models to induce immunological tolerance leading to reduced immune responses and protection from autoimmunity.
Müller, Werner +14 more
core +1 more source
The impact of T cell intrinsic antigen adaptation on peripheral immune tolerance. [PDF]
PLoS Biology, 2006 Overlapping roles have been ascribed for T cell anergy, clonal deletion, and regulation in the maintenance of peripheral immunological tolerance. A measurement of the individual and additive impacts of each of these processes on systemic tolerance is ...
Nevil J Singh +2 more
doaj +1 more source
The Role of Regulatory T Cells in Epicutaneous Immunotherapy for Food Allergy
Frontiers in Immunology, 2021 In recent decades, a rapid increase in the prevalence of food allergies has led to extensive research on novel treatment strategies and their mechanisms.
Guirong Liu +4 more
doaj +1 more source
The Plant Pathology Journal, 2013 Root colonization by Pseudomonas chlororaphis O6 induces systemic drought tolerance in Arabidopsis thaliana. Microarray analysis was performed using the 22,800-gene Affymetrix GeneChips to identify differentially-expressed genes from plants colonized ...
Song-Mi Cho +2 more
doaj +1 more source
Human rhinovirus infection induces local and systemic immunological tolerance in healthy volunteers [PDF]
Intensive Care Medicine Experimental, 2015 A large proportion of ICU patients suffer from respiratory virus infections. This is often complicated by secondary infections, suggesting increased vulnerability in these patients. Recent work has shown that in bacterial sepsis, a immunosuppressive state called “immunoparalysis” accounts for this increased vulnerability.
Koch, RM +7 more
openaire +1 more source
Role of regulatory T cells in immune tolerance [PDF]
, 2009 In this present work, we investigated the role of dendritic cells (DC) and regulatory T cells (Treg) in immune tolerance as well as their potential in the treatment of autoimmune or graft versus host (GvH) diseases.
Swee, Lee Kim
core +1 more source
Frontiers in Plant Science, 2018 Systemic wound response (SWR), a well-characterized systemic signaling response, plays crucial roles in plant defense responses. Progress in understanding of the SWR in abiotic stress has also been aided by the researchers.
Tong Si +8 more
doaj +1 more source