Results 31 to 40 of about 5,003,944 (244)
The zinc finger transcription factor Early Growth Response 2 (Egr-2) is an intrinsic regulator of T cell tolerance and homeostasis [PDF]
PhDTolerance of T cells to self-antigen is crucial to prevent the development of autoimmune disease. How self-tolerance is controlled at the transcriptional level is, however, unknown. We discovered that the transcription factor Early Growth Response 2
Symonds, Alistair
core +4 more sources
The symbiotic relationship between legumes and nitrogen-fixing rhizobia induces local and systemic responses, which ultimately lead to nodule formation.
Tadeo F. Fernandez-Göbel +8 more
doaj +1 more source
Certain plant growth promoting bacteria have ability to ameliorate abiotic and/or biotic stressors, which can be exploited to enhance plant growth and productivity of the plants under stress conditions.
Rajnish P. Singh, Prabhat N. Jha
doaj +1 more source
The ability of natural tolerance to be applied to allogeneic tissue: determinants and limits
Background Transplant rejection has been considered to occur primarily because donor antigens are not present during the development of the recipient's immune system to induce tolerance. Thus, transplantation prior to recipient immune system development (
Razavy Haide +3 more
doaj +1 more source
Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells
Summary: Many promising vaccine candidates and licensed vaccines lead to variable immune responses within humans. Studies suggest that environmental exposures in the gastrointestinal tract could contribute to a reduction in vaccine efficacy via immune ...
Nicole B. Potchen +9 more
doaj +1 more source
Specific oral tolerance induction in children with very severe cow's milk-induced reactions.
The aim of this study was to evaluate the safety and efficacy of specific oral tolerance induction (SOTI) for children with severe CMP-induced systemic ...
VENTURA, ALESSANDRO +6 more
core +1 more source
Strawberry (Fragaria × ananassa), with global production exceeding 9.8 million tons and a market value of USD 19 billion, is a major horticultural crop increasingly threatened by climate change.
Jin-Soo Son +5 more
doaj +1 more source
Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism
Summary: Cold-induced thermogenesis in endotherms demands adaptive thermogenesis fueled by mitochondrial respiration and Ucp1-mediated uncoupling in multilocular brown adipocytes (BAs).
Esther Paulo +10 more
doaj +1 more source
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
CD4-blockade can induce protection from peanut-induced anaphylaxis
Monoclonal antibodies (mAb) have been shown effective in inducing immune tolerance in a range of animal models of autoimmunity, allergy, and transplantation.
Joana eDuarte +3 more
doaj +1 more source

