Results 11 to 20 of about 695,844 (230)

Rapid Construction of Stable Infectious Full-Length cDNA Clone of Papaya Leaf Distortion Mosaic Virus Using In-Fusion Cloning

open access: yesViruses, 2015
Papaya leaf distortion mosaic virus (PLDMV) is becoming a threat to papaya and transgenic papaya resistant to the related pathogen, papaya ringspot virus (PRSV).
Wentao Shen, Decai Tuo
exaly   +4 more sources

A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development [PDF]

open access: yesmBio, 2016
An arthropod-borne virus, Zika virus (ZIKV), has recently emerged as a major human pathogen. Associated with complications during perinatal development and Guillain-Barré syndrome in adults, ZIKV raises new challenges for understanding the molecular ...
Konstantin A. Tsetsarkin   +8 more
doaj   +3 more sources

Construction and characterization of an infectious clone of coxsackievirus A16 [PDF]

open access: yesVirology Journal, 2011
Background Coxsackievirus A16 (CVA16) is a member of the Enterovirus genus of the Picornaviridae family and it is a major etiological agent of hand, foot, and mouth disease (HFMD), which is a common illness affecting children.
Liu Fei   +4 more
doaj   +2 more sources

Development and biological characterization of an infectious cDNA clone of NADC34-like PRRSV [PDF]

open access: yesFrontiers in Microbiology
IntroductionPorcine Reproductive and Respiratory Syndrome virus (PRRSV) causes high abortion rates in gestating sows and stillbirths, as well as high piglet mortality, seriously jeopardizing the pig industry in China and worldwide.MethodsIn this study ...
Yafang Lin   +9 more
doaj   +2 more sources

Construction and characterization of an infectious cDNA clone of coxsackievirus A 10 [PDF]

open access: yesVirology Journal, 2019
Background Coxsackievirus A10 (CA10) constitutes one of the four major pathogens causing hand, foot and mouth disease in infants. Infectious clones are of great importance for studying viral gene functions and pathogenic mechanism.
Qiliang Liu   +7 more
doaj   +2 more sources

A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

open access: yesEBioMedicine, 2017
A purified inactivated vaccine (PIV) using the Zika virus (ZIKV) Puerto Rico strain PRVABC59 showed efficacy in monkeys, and is currently in a phase I clinical trial. High-yield manufacture of this PIV is essential for its development and vaccine access.
Yujiao Yang   +10 more
doaj   +2 more sources

The preparation of an infectious full-length cDNA clone of Saffold virus [PDF]

open access: yesVirology Journal, 2011
The pathogenicity of Saffold virus (SAFV) among humans still remains unclear, although it was identified as a novel human cardiovirus in 2007. In order to encourage the molecular pathogenetic studies of SAFV, we generated an infectious cDNA clone of SAFV
Okuwa Takako   +6 more
doaj   +2 more sources

Construction and Biological Characterization of Papaya Leaf Curl Guangdong Virus Infectious cDNA Clone [PDF]

open access: yesMicrobial Biotechnology
Papaya leaf curl Guangdong virus (PaLCuGDV), a member of the genus Begomovirus, poses a significant threat to passion fruit (Passiflora edulis) cultivation. A recent field survey in the Rongjiang area of Guizhou Province revealed a high natural infection
Sheng Xu   +4 more
doaj   +2 more sources

Generation of an infectious clone of HuN4-F112, an attenuated live vaccine strain of porcine reproductive and respiratory syndrome virus

open access: yesVirology Journal, 2011
Background Nowadays, PRRS has become one of the most economically important infectious diseases of pig worldwide. To better characterize and understand the molecular basis of PRRSV virulence determinants, it would be important to develop the infectious ...
Zhang Shanrui   +6 more
doaj   +2 more sources

Construction of Infectious cDNA Clone of a Chrysanthemum stunt viroid Korean Isolate [PDF]

open access: yesThe Plant Pathology Journal, 2014
Chrysanthemum stunt viroid (CSVd), a noncoding infectious RNA molecule, causes seriously economic losses of chrysanthemum for 3 or 4 years after its first infection.
Ju-Yeon Yoon   +3 more
doaj   +2 more sources

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