Results 91 to 100 of about 18,204 (247)

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Inflammaging, immunosenescence, and cardiovascular aging: insights into long COVID implications

Frontiers in Cardiovascular Medicine
Aging leads to physiological changes, including inflammaging—a chronic low-grade inflammatory state with significant implications for various physiological systems, particularly for cardiovascular health.
Ludmila Müller, Svetlana Di Benedetto
doaj   +1 more source

Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age [PDF]

, 2015
Background: Chronic low-grade inflammation is considered a driver of many age-related disorders, including vascular diseases (inflammaging). Inhibition of autophagic capacity with ageing was postulated to generate a pro-inflammatory condition via ...
Böckler, Dittmar, Dihlmann, Susanne, Hakimi, Maani, Wortmann, Markus, Wu, Xiaoyu, Zhang, Jian   +5 more
core   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, EarlyView.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source

Ganoderma Microsporum Immunomodulatory Protein Alleviates Inflammaging and Oxidative Stress in Diabetes-Associated Periodontitis via Nrf2 Signaling Activation: An In Vitro Study

Antioxidants
Periodontitis, characterized by inflammation and loss of periodontal tissue, is a significant health complication for individuals with diabetes mellitus (DM).
Ni-Yu Su, Min Yee Ng, Heng-Yi Liao, Yi-Wen Liao, Movina Wu, Shih-Chi Chao, Cheng-Chia Yu, Yu-Chao Chang   +7 more
doaj   +1 more source

Breast Tissue Biology Expands the Possibilities for Prevention of Age-Related Breast Cancers. [PDF]

, 2019
Preventing breast cancer before it is able to form is an ideal way to stop breast cancer. However, there are limited existing options for prevention of breast cancer.
Fresques, Tara, LaBarge, Mark A, Preto, Sandy, Samson, Susan, Shalabi, Sundus, Stampfer, Martha R, Zirbes, Arrianna   +6 more
core  

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

International Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang, Hong Zhang, Chengming Zhang, Wencai Jiang, Luonan Chen, Yimei Tan, Ying Zou, Xuelan Gu   +7 more
wiley   +1 more source

Role of inflammaging in the development of chronic heart failure and osteoporosis: A literature review [PDF]

КардиоСоматика
The interaction between heart failure (HF) and osteoporosis in a multimorbid patient is a relevant complication in the aging population. The concept of inflammaging (inflammatory aging) allows us to consider the prolonged process of subclinical ...
Vera N. Larina, Ekaterina S. Shcherbina
doaj   +1 more source

Reversing T cell immunosenescence: why, who, and how [PDF]

, 2018
Immunosenescence is the term commonly used to describe the multifaceted phenomenon encompassing all changes occurring in the immune system during aging.
Aspinall, Richard, Govind, Sheila, Lang, Pierre   +2 more
core  

Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation [PDF]

, 2018
The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments.
Chatzinikolaou, Athanasios, Chondrogianni, Niki, Deli, Chariklia K, Draganidis, Dimitrios, Fatouros, Ioannis G, Georgakouli, Kalliopi, Jamurtas, Athanasios Z, Karagounis, Leonidas G, Koutedakis, Yiannis, Laschou, Vasiliki C, Michalopoulou, Maria, Papadopoulos, Constantinos, Papanikolaou, Konstantinos, Stampoulis, Theodoros, Tsimeas, Panagiotis   +14 more
core   +3 more sources